Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | CCR9 | P51686 | 2/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454352 | 0.81 | HDAC1 (0.39) | NOTUMKMT2ACYP2C19MEN1CYP3A4 | |
| SCHEMBL20249276 | 0.80 | AOC3 (0.37) | NOTUMMLYCDGPBAR1CCR9 | |
| SCHEMBL7733716 | 0.78 | NOTUM (0.52) | NOTUMMLYCDKMT2ACYP2C19MEN1 | |
| SCHEMBL19104074 | 0.76 | ALDH1A1 (0.42) | MLYCDKMT2AMEN1CYP3A4SMN1; SMN2 | |
| SCHEMBL16446650 | 0.73 | KMT2A (0.38) | NOTUMKMT2ACYP2C19MEN1CYP3A4 | |
| SCHEMBL20249216 | 0.73 | PDK2 (0.40) | KMT2AMEN1GPBAR1 | |
| SCHEMBL31222337 | 0.69 | NOTUM (0.49) | NOTUMKMT2ACYP2C19MEN1CYP3A4 | |
| SCHEMBL21653748 | 0.69 | NOTUM (0.45) | NOTUMKMT2ACYP2C19MEN1CYP3A4 | |
| SCHEMBL15539862 | 0.69 | NOTUM (0.49) | NOTUMKMT2ACYP2C19MEN1CYP3A4 | |
| SCHEMBL15540001 | 0.69 | NOTUM (0.45) | NOTUMKMT2ACYP2C19MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963445-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |
| US-9963445-B2 | Chemical compounds | SYNGENTA LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |
| US-20160159781-A1 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159781-A1 | CHEMICAL COMPOUNDS | DDT, CBR3, CYP1B1 | NOTUM 553/4885MLYCD 1273/4885KMT2A 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.