Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.59 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | FER | P16591 | 1/20 | 0.59 |
| ▸ | LTK | P29376 | 1/20 | 0.59 |
| ▸ | CDK8 | P49336 | 1/20 | 0.59 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30462618 | 1.00 | LRRK2 (0.59) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL181764 | 1.00 | LRRK2 (0.59) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL29268797 | 0.87 | ACVR1 (0.48) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL29268749 | 0.84 | ACVR1 (0.46) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL29268818 | 0.81 | ACVR1 (0.48) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL24254102 | 0.81 | ALDH1A1 (0.58) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL31108400 | 0.79 | LRRK2 (0.46) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL11879510 | 0.79 | ACVR1 (0.52) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL6255304 | 0.79 | LRRK2 (0.58) | LRRK2ACVR1PDGFRAFERLTK | |
| SCHEMBL30513887 | 0.79 | ACVR1 (0.52) | LRRK2ACVR1PDGFRAFERLTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | WO | disclosed |