SCHEMBL181764

SCHEMBL181764

c1ccc2c(c1)Nc1ccccc1-c1ccccc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 3/20 0.59
ACVR1 Q04771 2/20 0.59
PDGFRA P16234 1/20 0.59
FER P16591 1/20 0.59
LTK P29376 1/20 0.59
CDK8 P49336 1/20 0.59
DYRK1B Q9Y463 1/20 0.59
MAOA P21397 3/20 0.52
MAOB P27338 1/20 0.52
MAPT P10636 6/20 0.48
GAA P10253 2/20 0.48
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
BCHE P06276 3/20 0.46
ACHE P22303 2/20 0.46
NOX1 Q9Y5S8 2/20 0.46
POLB P06746 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ALOX5 P09917 1/20 0.46
CYP1A2 P05177 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17816635 1.00 LRRK2 (0.59) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL30462618 1.00 LRRK2 (0.59) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL29268797 0.87 ACVR1 (0.48) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL29268749 0.84 ACVR1 (0.46) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL29268818 0.81 ACVR1 (0.48) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL24254102 0.81 ALDH1A1 (0.58) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL31108400 0.79 LRRK2 (0.46) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL11879510 0.79 ACVR1 (0.52) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL6255304 0.79 LRRK2 (0.58) LRRK2ACVR1PDGFRAFERLTK
SCHEMBL30513887 0.79 ACVR1 (0.52) LRRK2ACVR1PDGFRAFERLTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11289660-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2022-03-29 US claimed
US-20200411772-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-12-31 US claimed
US-10807996-B2 Material for organic electroluminescent element and organic electroluminescent element in which same is used NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-10-20 US claimed
US-10636981-B2 Material for organic electroluminescent element and organic electroluminescent element using the same NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-04-28 US claimed
US-10622570-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-04-14 US claimed
US-10476006-B2 Compound and organic electronic device using the same SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) 2019-11-12 US claimed
EP-3281936-B1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) 2019-10-09 EP claimed
EP-3530658-A2 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2019-08-28 EP claimed
US-20190237679-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-01 US claimed
US-10283721-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-05-07 US claimed
EP-3247765-B1 AZOLES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2018-11-07 EP claimed
US-20180047908-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME NICHEM FINE TECHNOLOGY CO., LTD. (TW) 2018-02-15 US claimed
EP-3281936-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME Nichem Fine Technology Co., Ltd. (TW) 2018-02-14 EP claimed
EP-3247773-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS cynora GmbH (DE) 2017-11-29 EP claimed
EP-3247765-A1 AZOLES FOR USE IN OPTOELECTRONIC COMPONENTS cynora GmbH (DE) 2017-11-29 EP claimed
US-20170117482-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-04-27 US claimed
WO-2016116529-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO claimed
WO-2016116485-A1 AZOLES FOR USE IN OPTOELECTRONIC COMPONENTS CYNORA GMBH (DE) 2016-07-28 WO claimed
US-20050164032-A1 Organic electroluminescent element FUJI PHOTO FILM CO., LTD. 2005-07-28 US claimed
US-6476221-B1 Tribenzazepine compound and production method thereof FUJI PHOTO FILM CO., LTD. (JP) 2002-11-05 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10622570-B2 Organic electroluminescent element NR2E3, ESR1, NCOR2 LRRK2 970/4885ACVR1 2072/4885PDGFRA 4208/4885
US-10807996-B2 Material for organic electroluminescent element and organic electroluminescent element in which same is used LEF1, EXOC1, EFNA1 LRRK2 310/4885ACVR1 487/4885PDGFRA 3277/4885
US-11289660-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CRY2, SUN2 LRRK2 1526/4885ACVR1 2142/4885PDGFRA 3489/4885
US-20170117482-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME L1CAM, LEF1, LAGE3 LRRK2 784/4885ACVR1 904/4885PDGFRA 4501/4885
US-10476006-B2 Compound and organic electronic device using the same ESR1, AOC2, PIEZO1 LRRK2 2489/4885ACVR1 2787/4885PDGFRA 4178/4885
US-10636981-B2 Material for organic electroluminescent element and organic electroluminescent element using the same LEF1, EDF1, CELF2 LRRK2 491/4885ACVR1 1955/4885PDGFRA 2941/4885
US-20180047908-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME ESR1, AOC2, PIEZO1 LRRK2 2489/4885ACVR1 2787/4885PDGFRA 4178/4885
US-10283721-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same LEF1, MLLT1, BMI1 LRRK2 254/4885ACVR1 3527/4885PDGFRA 4512/4885
US-20190237679-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, SUN2 LRRK2 1526/4885ACVR1 2142/4885PDGFRA 3489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.