Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | PRKDC | P78527 | 5/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PRKCG | P05129 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19054456 | 0.86 | ALOX5 (0.45) | ALOX5PRKDCGGPS1PTGES2PIK3CD | |
| SCHEMBL16631812 | 0.85 | CDK2 (0.35) | ALOX5CDK2 | |
| SCHEMBL22813814 | 0.85 | ALOX5 (0.44) | ALOX5PRKDCGGPS1PTGES2PIK3CD | |
| SCHEMBL31593186 | 0.84 | ALOX5 (0.59) | ALOX5PRKDCCDK2GGPS1PTGES2 | |
| SCHEMBL75000 | 0.84 | ALOX5 (0.59) | ALOX5PRKDCCDK2GGPS1PTGES2 | |
| SCHEMBL30035488 | 0.84 | ALOX5 (0.59) | ALOX5PRKDCCDK2GGPS1PTGES2 | |
| SCHEMBL22698886 | 0.83 | ALOX5 (0.46) | ALOX5PRKDCGGPS1PTGES2PIK3CD | |
| SCHEMBL10307237 | 0.83 | ALOX5 (0.57) | ALOX5PRKDCCDK2GGPS1PTGES2 | |
| SCHEMBL75948 | 0.82 | ALOX5 (0.56) | ALOX5PRKDCCDK2GGPS1PTGES2 | |
| SCHEMBL29407300 | 0.82 | ALOX5 (0.56) | ALOX5PRKDCCDK2GGPS1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087017-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2016-06-09 | — | — | WO | disclosed |