SCHEMBL10307237

SCHEMBL10307237

c1ccc2c(c1)oc1c(-c3ccc(Nc4ccc(-c5ccc(Nc6ccc(-c7cccc8c7oc7ccccc78)cc6)cc5)cc4)cc3)cccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.57
GGPS1 O95749 1/20 0.42
EPHX2 P34913 1/20 0.42
PRKDC P78527 5/20 0.42
PTGES2 Q9H7Z7 1/20 0.42
CDK2 P24941 1/20 0.41
KDM4E B2RXH2 4/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 4/20 0.39
HSD17B10 Q99714 3/20 0.39
CASP3 P42574 2/20 0.39
SENP7 Q9BQF6 2/20 0.39
LMNA P02545 2/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31593186 0.98 ALOX5 (0.59) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL30035488 0.98 ALOX5 (0.59) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL75000 0.98 ALOX5 (0.59) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL30436413 0.97 ALOX5 (0.55) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL29405383 0.97 ALOX5 (0.55) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL10109886 0.97 ALOX5 (0.55) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL29665202 0.97 ALOX5 (0.55) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL75955 0.97 ALOX5 (0.55) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL10109884 0.97 ALOX5 (0.55) ALOX5GGPS1EPHX2PRKDCPTGES2
SCHEMBL75948 0.95 ALOX5 (0.56) ALOX5GGPS1EPHX2PRKDCPTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023219399-A1 COMPOUND, COATING COMPOSITION COMPRISING SAME, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR 주식회사 엘지화학 2023-11-16 WO disclosed
US-9972786-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-05-15 US disclosed
US-9972786-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-05-15 US disclosed
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-10 US disclosed
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-10 US disclosed
US-9054322-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-9054322-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-12 US disclosed
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-12 US disclosed
US-20110278551-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-17 US disclosed
US-20110278551-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-17 US disclosed
US-7998596-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-08-16 US disclosed
US-7998596-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-08-16 US disclosed
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2009-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, SLC7A5, SLC18A1 ALOX5 1326/4885GGPS1 4077/4885EPHX2 617/4885
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC7A5, ALKBH3, TYR ALOX5 1384/4885GGPS1 4116/4885EPHX2 623/4885
US-20110278551-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC7A5, ALKBH3, TYR ALOX5 1384/4885GGPS1 4116/4885EPHX2 623/4885
US-20090066235-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME DDC, TYR, EML4 ALOX5 3073/4885GGPS1 3330/4885EPHX2 1284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.