SCHEMBL1781674

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1783498	0.88	HCAR3 (0.43)	HCAR3PIK3CGOGALMNAGAA
	SCHEMBL1783723	0.88	OGA (0.34)	HCAR3PIK3CGOGAPIK3CAPIK3CB
	SCHEMBL1117984	0.86	HCAR3 (0.40)	HCAR3PIK3CGADRA1AALDH1A1PI4KB
	SCHEMBL1784359	0.85	HCAR3 (0.40)	HCAR3PIK3CGKDM4EALDH1A1OGA
	SCHEMBL1783449	0.85	HCAR3 (0.45)	HCAR3PIK3CGKDM4EALDH1A1OGA
	SCHEMBL1782452	0.83	HCAR3 (0.44)	HCAR3PIK3CGALDH1A1LMNAGAA
	SCHEMBL1117926	0.83	HCAR3 (0.37)	HCAR3PIK3CGALDH1A1LMNAMAPT
	SCHEMBL1783767	0.83	PIK3CG (0.39)	PIK3CGOGALMNAGAAMAPT
	SCHEMBL1782768	0.83	HCAR3 (0.43)	HCAR3PIK3CGKDM4EALDH1A1OGA
	SCHEMBL1782298	0.82	PIK3CG (0.50)	PIK3CGKDM4EALDH1A1OGALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.