SCHEMBL1782452

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1784359	0.90	HCAR3 (0.40)	HCAR3PIK3CGPIK3CDPIK3CAPIK3CB
	SCHEMBL1782768	0.87	HCAR3 (0.43)	HCAR3PIK3CGPIK3CDPIK3CAPIK3CB
	SCHEMBL1783498	0.87	HCAR3 (0.43)	HCAR3PIK3CGPIK3CDPIK3CAPIK3CB
	SCHEMBL1783767	0.87	PIK3CG (0.39)	PI4KBPIK3CGPIK3CDPIK3CAPIK3CB
	SCHEMBL1117947	0.87	HCAR3 (0.42)	HCAR3PRKAB2PRKAG1PRKAA2PRKAA1
	SCHEMBL1781491	0.86	PIK3CG (0.42)	PIK3CGPIK3CDPIK3CAPIK3CBLMNA
	SCHEMBL13690398	0.85	PIK3CA (0.43)	PI4KBPIK3CGPIK3CDPIK3CAPIK3CB
	SCHEMBL1781217	0.85	PIK3CG (0.43)	PIK3CGPIK3CDPIK3CAPIK3CBALDH1A1
	SCHEMBL1783223	0.85	OGA (0.42)	PIK3CGPIK3CDPIK3CAPIK3CBLMNA
	SCHEMBL1783449	0.84	HCAR3 (0.45)	HCAR3PIK3CGPIK3CDPIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.