Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 18/20 | 0.92 |
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.92 |
| ▸ | GAA | P10253 | 12/20 | 0.92 |
| ▸ | MAPT | P10636 | 10/20 | 0.92 |
| ▸ | GLA | P06280 | 9/20 | 0.92 |
| ▸ | HTT | P42858 | 5/20 | 0.92 |
| ▸ | LMNA | P02545 | 4/20 | 0.92 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.92 |
| ▸ | RAB9A | P51151 | 1/20 | 0.92 |
| ▸ | HPGD | P15428 | 12/20 | 0.79 |
| ▸ | SAE1 | Q9UBE0 | 3/20 | 0.78 |
| ▸ | UBA2 | Q9UBT2 | 3/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | CASP1 | P29466 | 3/20 | 0.67 |
| ▸ | CASP7 | P55210 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817473 | 1.00 | KDM4E (0.92) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL6981187 | 0.96 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL6981236 | 0.91 | KDM4E (0.88) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL15256914 | 0.88 | SAE1 (1.00) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL15256901 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL15256861 | 0.78 | SAE1 (0.77) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL15256869 | 0.77 | KDM4E (0.75) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL15256919 | 0.77 | KDM4E (0.68) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL6981812 | 0.76 | SAE1 (0.89) | KDM4EALDH1A1GAAMAPTGLA | |
| SCHEMBL15256904 | 0.73 | KDM4E (0.89) | KDM4EALDH1A1GAAMAPTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229811-B1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GRI BIO INC (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | KDM4E 812/4885ALDH1A1 999/4885GAA 1932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.