SCHEMBL17817809

SCHEMBL17817809

Brc1ccc(-c2nc3ccccc3o2)c(OCc2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SGMS2 Q8NHU3 5/20 0.52
KDM4E B2RXH2 4/20 0.50
MAPT P10636 4/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TSHR P16473 1/20 0.50
KDM6B O15054 1/20 0.44
KDM6A O15550 1/20 0.44
ALDH1A1 P00352 3/20 0.43
HPGD P15428 3/20 0.43
USP2 O75604 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
SLC6A4 P31645 1/20 0.42
BRD4 O60885 1/20 0.41
P2RY14 Q15391 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HSD17B10 Q99714 2/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19831028 0.90 SGMS2 (0.52) SGMS2KDM4EMAPTMEN1KMT2A
SCHEMBL30835032 0.90 SGMS2 (0.52) SGMS2KDM4EMAPTMEN1KMT2A
SCHEMBL20505130 0.85 MAPT (0.52) KDM4EMAPTMEN1KMT2ATSHR
SCHEMBL28561681 0.84 SGMS2 (0.70) SGMS2KDM4EMAPTKDM6BKDM6A
SCHEMBL30834990 0.80 KDM6B (0.46) SGMS2KDM4EMAPTMEN1KMT2A
SCHEMBL28597246 0.80 KDM6B (0.46) SGMS2KDM4EMAPTMEN1KMT2A
SCHEMBL28609439 0.78 SGMS2 (0.47) SGMS2KDM4EMAPTALDH1A1HPGD
SCHEMBL3136330 0.78 KDM4E (0.50) SGMS2KDM4EMAPTTSHRALDH1A1
SCHEMBL17817808 0.78 SGMS2 (0.45) SGMS2KDM4EMAPTMEN1KMT2A
SCHEMBL18875231 0.77 MAPT (0.63) KDM4EMAPTMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9957260-B2 Organic metal complex, light emitting material, delayed fluorescent material, and organic light emitting device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-05-01 US disclosed
US-9957260-B2 Organic metal complex, light emitting material, delayed fluorescent material, and organic light emitting device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2018-05-01 US disclosed
US-20160185765-A1 ORGANIC METAL COMPLEX, LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE DYDEN CO (JP) 2016-06-30 US disclosed
US-20160185765-A1 ORGANIC METAL COMPLEX, LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE DYDEN CO (JP) 2016-06-30 US disclosed
US-20160185765-A1 ORGANIC METAL COMPLEX, LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE DYDEN CO (JP) 2016-06-30 US disclosed
EP-3031805-A1 ORGANIC METAL COMPLEX, LUMINESCENT MATERIAL, DELAYED PHOSPHOR AND ORGANIC LIGHT EMITTING ELEMENT Kyushu University, National University Corporation (JP) 2016-06-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160185765-A1 ORGANIC METAL COMPLEX, LIGHT EMITTING MATERIAL, DELAYED FLUORESCENT MATERIAL, AND ORGANIC LIGHT EMITTING DEVICE OR10J3, SOD1, H1-10 SGMS2 3931/4885KDM4E 2408/4885MAPT 3159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.