Glutarate

Glutarate

SCHEMBL17818645

CC(C)O.CC(C)O.O=C(O)CCCC(=O)O.O=C(O)CCCC(=O)O.[Ti]

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.65
LMNA P02545 2/20 0.56
TSHR P16473 6/20 0.53
NFKB1 P19838 1/20 0.53
PMP22 Q01453 1/20 0.53
AKR1B1 P15121 1/20 0.50
GPR84 Q9NQS5 7/20 0.48
PPARG P37231 6/20 0.48
PPARD Q03181 6/20 0.48
PPARA Q07869 6/20 0.48
HDAC11 Q96DB2 5/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
PTPN1 P18031 2/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
MEN1 O00255 1/20 0.48
ESR1 P03372 1/20 0.48
ALOX15 P16050 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL17823297 0.97 SLC22A6 (0.69) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL28304104 0.91 LMNA (0.69) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL25265281 0.91 LMNA (0.69) SLC22A6LMNATSHRNFKB1PMP22
Isopropyl Alcohol SCHEMBL29235060 0.88 TSHR (0.71) SLC22A6LMNATSHRNFKB1PMP22
Sebacic Acid SCHEMBL27860431 0.88 TSHR (0.71) SLC22A6LMNATSHRNFKB1PMP22
Octanedioate SCHEMBL28590543 0.88 TSHR (0.71) SLC22A6LMNATSHRNFKB1PMP22
Isopropyl Alcohol SCHEMBL29137855 0.88 TSHR (0.71) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL28852051 0.86 SLC22A6 (0.61) SLC22A6LMNATSHRNFKB1PMP22
Glutarate SCHEMBL5874258 0.86 SLC22A6 (0.61) SLC22A6LMNATSHRNFKB1PMP22
Adipic Acid SCHEMBL30288555 0.85 LMNA (0.69) SLC22A6LMNATSHRNFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3230293-B1 HIGH SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES GELEST TECH INC (US) 2019-10-16 EP claimed
US-9879159-B2 High-speed moisture-cure hybrid siloxane/silsesquioxane-urethane and siloxane/silsesquioxane-epoxy systems with adhesive properties GELEST TECHNOLOGIES, INC. (US) 2018-01-30 US claimed
US-20160168429-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES GELEST, INC. 2016-06-16 US claimed
US-10995244-B2 High-speed moisture-cure hybrid siloxane/silsesquioxane-urethane and siloxane/silsesquioxane-epoxy systems with adhesive properties GELEST TECHNOLOGIES, INC. (US) 2021-05-04 US disclosed
EP-3230293-B1 HIGH SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES GELEST TECH INC (US) 2019-10-16 EP disclosed
US-20180066165-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES GELEST, INC. 2018-03-08 US disclosed
US-9879159-B2 High-speed moisture-cure hybrid siloxane/silsesquioxane-urethane and siloxane/silsesquioxane-epoxy systems with adhesive properties GELEST TECHNOLOGIES, INC. (US) 2018-01-30 US disclosed
EP-3230293-A1 HIGH SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES Gelest Technologies Inc. (US) 2017-10-18 EP disclosed
US-20160168429-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES GELEST, INC. 2016-06-16 US disclosed
WO-2016094186-A1 HIGH SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES GELEST TECHNOLOGIES, INC. (US) 2016-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10995244-B2 High-speed moisture-cure hybrid siloxane/silsesquioxane-urethane and siloxane/silsesquioxane-epoxy systems with adhesive properties PCNA, ICAM1, CCNO SLC22A6 4337/4885LMNA 2578/4885TSHR 4837/4885
US-20180066165-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES PCNA, ICAM1, CCNO SLC22A6 4337/4885LMNA 2578/4885TSHR 4837/4885
US-20160168429-A1 HIGH-SPEED MOISTURE-CURE HYBRID SILOXANE/SILSESQUIOXANE-URETHANE AND SILOXANE/SILSESQUIOXANE-EPOXY SYSTEMS WITH ADHESIVE PROPERTIES PCNA, ICAM1, CCNO SLC22A6 4337/4885LMNA 2578/4885TSHR 4837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.