Glutarate

Glutarate

SCHEMBL5874258

CC(N)O.O=C(O)CCCC(=O)O

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.61
GABRP O00591 3/20 0.56
GABRD O14764 3/20 0.56
GABRA1 P14867 3/20 0.56
GABRB1 P18505 3/20 0.56
GABRG2 P18507 3/20 0.56
GABRB3 P28472 3/20 0.56
GABRA5 P31644 3/20 0.56
GABRA3 P34903 3/20 0.56
GABRA2 P47869 3/20 0.56
GABRB2 P47870 3/20 0.56
GABRA4 P48169 3/20 0.56
GABRE P78334 3/20 0.56
GABRA6 Q16445 3/20 0.56
GABRG1 Q8N1C3 3/20 0.56
GABRG3 Q99928 3/20 0.56
GABRQ Q9UN88 3/20 0.56
LMNA P02545 3/20 0.53
TSHR P16473 5/20 0.50
HDAC11 Q96DB2 3/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adipic Acid SCHEMBL1836624 0.94 LMNA (0.61) SLC22A6GABRPGABRDGABRA1GABRB1
SCHEMBL1834739 0.92 TSHR (0.63) SLC22A6GABRPGABRDGABRA1GABRB1
Sebacic Acid SCHEMBL5875346 0.92 TSHR (0.63) SLC22A6GABRPGABRDGABRA1GABRB1
Glutarate SCHEMBL5546487 0.89 AKR1B1 (0.56) SLC22A6GABRPGABRDGABRA1GABRB1
Succinic Acid SCHEMBL1833787 0.88 GABRP (0.62) GABRPGABRDGABRA1GABRB1GABRG2
Glutarate SCHEMBL17823297 0.88 SLC22A6 (0.69) SLC22A6LMNATSHRHDAC11NFKB1
Valeric Acid SCHEMBL1830437 0.87 AKR1B1 (0.61) SLC22A6GABRPGABRDGABRA1GABRB1
Glutarate SCHEMBL27941460 0.86 SLC22A6 (0.58) SLC22A6GABRPGABRDGABRA1GABRB1
Glutarate SCHEMBL2868168 0.86 SLC22A6 (0.58) SLC22A6GABRPGABRDGABRA1GABRB1
Glutarate SCHEMBL17818645 0.86 SLC22A6 (0.65) SLC22A6LMNATSHRHDAC11NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed