Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 3/20 | 0.31 |
| ▸ | PDE1A | P54750 | 2/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15500234 | 0.92 | — | — | |
| SCHEMBL178263 | 0.86 | LMNA (0.35) | LMNAEGLN2EGLN1PTGS1EPHX2 | |
| SCHEMBL203415 | 0.83 | LMNA (0.36) | LMNAEGLN2EGLN1PTGS1EPHX2 | |
| SCHEMBL18892930 | 0.81 | FOLH1 (0.45) | FOLH1PTGS2 | |
| SCHEMBL19976546 | 0.80 | FOLH1 (0.49) | FOLH1PTGS2 | |
| SCHEMBL15500256 | 0.79 | FOLH1 (0.32) | FOLH1PTGS2 | |
| SCHEMBL17301761 | 0.78 | FOLH1 (0.48) | FOLH1PTGS2 | |
| SCHEMBL16252093 | 0.78 | MEN1 (0.32) | LMNA | |
| SCHEMBL19063171 | 0.78 | FOLH1 (0.35) | FOLH1PTGS2 | |
| SCHEMBL178148 | 0.77 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392659-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170183501-A1 | Cyanine Dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-06-29 | — | — | US | disclosed |
| US-9441270-B2 | Cyanine dyes | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-09-13 | — | — | US | disclosed |
| US-20150344950-A1 | Functionalized Cyanine Dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-9051263-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-06-09 | — | — | US | disclosed |
| US-20150072894-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-03-12 | — | — | US | disclosed |
| US-8889886-B2 | Cyanine dyes | PACIFIC BIOSCIENCES, INC. (US) | 2014-11-18 | — | — | US | disclosed |
| US-8669374-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2014-03-11 | — | — | US | disclosed |
| US-20120058469-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-08 | — | — | US | disclosed |
| US-20120052506-A1 | CYANINE DYES | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392659-B2 | Cyanine dyes | ABCG2, IK, ACR | LMNA 1823/4885EGLN2 2715/4885EGLN1 2931/4885 |
| US-20120052506-A1 | CYANINE DYES | ABCG2, IK, ACR | LMNA 1823/4885EGLN2 2715/4885EGLN1 2931/4885 |
| US-20120058482-A1 | FUNCTIONALIZED CYANINE DYES (PEG) | ACR, IK, EGFR | LMNA 2335/4885EGLN2 1534/4885EGLN1 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.