Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 12/20 | 0.39 |
| ▸ | ATM | Q13315 | 14/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17820154 | 0.90 | PIK3C3 (0.41) | PIK3C3ATMALDH1A1MAPTGAA | |
| SCHEMBL17828212 | 0.89 | PIK3C3 (0.40) | PIK3C3ATMALDH1A1MAPTGAA | |
| SCHEMBL17819826 | 0.88 | PIK3C3 (0.41) | PIK3C3ATMALDH1A1MAPTGAA | |
| SCHEMBL17820629 | 0.85 | PIK3C3 (0.39) | PIK3C3ATMALDH1A1MAPTGAA | |
| SCHEMBL17820826 | 0.80 | PIK3C3 (0.44) | PIK3C3ATMPRKDC | |
| SCHEMBL17819991 | 0.79 | PIK3C3 (0.45) | PIK3C3ATMALDH1A1GAAPRKDC | |
| SCHEMBL17820560 | 0.79 | PIK3C3 (0.45) | PIK3C3ATMALDH1A1PRKDCMEN1 | |
| SCHEMBL17820251 | 0.79 | ATM (0.44) | PIK3C3ATMALDH1A1MAPTGAA | |
| SCHEMBL17820764 | 0.78 | PIK3C3 (0.43) | PIK3C3ATMPRKDC | |
| SCHEMBL17828209 | 0.78 | PIK3C3 (0.49) | PIK3C3ATMALDH1A1PRKDCMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9586951-B2 | Morpholine derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168139-A1 | NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF | PRMT7, RBBP7, RER1 | PIK3C3 3047/4885ATM 3209/4885ALDH1A1 2519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.