Benzophenone

Benzophenone

SCHEMBL1781970

O=C(c1ccccc1)c1ccccc1.OC(c1ccccc1)c1ccccc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
TDP1 Q9NUW8 2/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
SRD5A2 P31213 2/20 0.56
ATM Q13315 1/20 0.56
LMNA P02545 5/20 0.56
CES2 O00748 1/20 0.56
CES1 P23141 1/20 0.56
MAPT P10636 3/20 0.53
PTGS1 P23219 3/20 0.53
PTGS2 P35354 3/20 0.53
CXCR1 P25024 2/20 0.53
CXCR2 P25025 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
MAPK1 P28482 2/20 0.53
RECQL P46063 1/20 0.53
KDM4E B2RXH2 1/20 0.53
CYP3A4 P08684 1/20 0.53
HPGD P15428 1/20 0.53
PMP22 Q01453 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22129542 0.93 ALDH1A1 (0.56) ALDH1A1TDP1L3MBTL1SRD5A2ATM
SCHEMBL15264145 0.90 MAPT (0.64) ALDH1A1TDP1L3MBTL1ATMLMNA
SCHEMBL5161936 0.87 SRD5A2 (0.55) ALDH1A1SRD5A2LMNACES2CES1
SCHEMBL20696554 0.87 ATM (0.64) ALDH1A1TDP1L3MBTL1ATMLMNA
SCHEMBL23018871 0.87 ATM (0.64) ALDH1A1TDP1L3MBTL1ATMLMNA
Diphenylmethanol SCHEMBL28538283 0.86 TSHR (0.67) TDP1L3MBTL1SRD5A2LMNACES2
Diphenylmethanol SCHEMBL9188301 0.85 LMNA (0.59) TDP1L3MBTL1SRD5A2LMNACES2
Diphenylmethanol SCHEMBL6434457 0.82 SMN1; SMN2 (0.61) L3MBTL1LMNASMN1; SMN2MAPK1KDM4E
Diphenylmethanol SCHEMBL11564700 0.82 SMN1; SMN2 (0.61) L3MBTL1LMNASMN1; SMN2MAPK1KDM4E
Diphenylmethanol SCHEMBL10868602 0.82 SMN1; SMN2 (0.61) L3MBTL1LMNASMN1; SMN2MAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106810429-A A kind of method for refining benzophenone 青岛森美克化工技术有限公司 2017-06-09 CN disclosed
US-8735167-B2 Photoinduced signal amplification through externally sensitized photofragmentation in masked photosensitizers and photoamplified fluorescence turn-off system COLORADO SEMINARY, WHICH OWNS AND OPERATES THE UNIVERSITY OF DENVER (US) 2014-05-27 US disclosed
US-20110117667-A1 PHOTOINDUCED SIGNAL AMPLIFICATION THROUGH EXTERNALLY SENSITIZED PHOTOFRAGMENTATION IN MASKED PHOTOSENSITIZERS AND PHOTOAMPLIFIED FLUORESCENCE TURN-OFF SYSTEM COLORADO SEMINARY, WHICH OWNS AND OPERATES THE UNIVERSITY OF DENVER 2011-05-19 US disclosed
WO-2009026313-A1 PHOTOINDUCED SIGNAL AMPLIFICATION THROUGH EXTERNALLY SENSITIZED PHOTOFRAGMENTATION IN MASKED PHOTOSENSITIZERS AND PHOTOAMPLIFIED FLUORESCENCE TURN-OFF SYSTEM COLORADO SEMINARY, WHICH OWNS AND OPERATES THE UNIVERSITY OF DENVER (US) 2009-02-26 WO disclosed
US-4498963-A Photopolymerizable composition containing perester photoinitiator and photopolymerization process BOWLING GREEN STATE UNIVERSITY (US) 1985-02-12 US disclosed
US-4416826-A PHOTOINITIATORS FOR POLYMERIZATION OF ETHYLENICALLY UNSATURATED MATERIALS BOWLING GREEN STATE UNIVERSITY, AN EDUCATIONAL INSTITUTION OF OH. 1983-11-22 US disclosed