Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029723 | 0.93 | ALOX15 (0.46) | PAOXSIGMAR1ALDH1A1TSHRALOX15 | |
| SCHEMBL27699518 | 0.85 | — | — | |
| SCHEMBL9434876 | 0.85 | ALOX15 (0.50) | ALDH1A1TSHRALOX15PIM1 | |
| SCHEMBL14357082 | 0.85 | ALOX15 (0.41) | PAOXSIGMAR1ALOX15PIM1 | |
| SCHEMBL8471267 | 0.84 | HRH3 (0.56) | SIGMAR1ALDH1A1TSHRALOX15 | |
| SCHEMBL8997844 | 0.84 | PAOX (0.38) | PAOXSIGMAR1ALDH1A1ALOX15USP2 | |
| SCHEMBL134397 | 0.83 | PIM1 (0.39) | PAOXSIGMAR1ALDH1A1PIM1 | |
| SCHEMBL14142584 | 0.83 | PIM1 (0.39) | PAOXSIGMAR1ALDH1A1PIM1 | |
| SCHEMBL19212956 | 0.83 | PIM1 (0.39) | PAOXSIGMAR1ALDH1A1PIM1 | |
| SCHEMBL25961628 | 0.83 | SIGMAR1 (0.44) | SIGMAR1ALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753613-B1 | DERIVATIVES OF XANTHONE COMPOUNDS | AGENCY SCIENCE TECH & RES (SG) | 2020-03-04 | — | — | EP | disclosed |
| US-8927613-B2 | Cellular elastomer with little tendency toward creep at high temperatures | BASF SE (DE) | 2015-01-06 | — | — | US | disclosed |
| US-20110118373-A1 | CELLULAR ELASTOMER WITH LITTLE TENDENCY TOWARD CREEP AT HIGH TEMPERATURES | BASF SE (DE) | 2011-05-19 | — | — | US | disclosed |