SCHEMBL1782152

SCHEMBL1782152

OC[C@H]1OC(C(O)[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C(O)C2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 2/20 0.44
LGALS3 P17931 2/20 0.44
LGALS9 O00182 1/20 0.44
LGALS8 O00214 1/20 0.44
ALDH1A1 P00352 2/20 0.36
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
PYGB P11216 6/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9231902 1.00 LGALS1 (0.44) LGALS1LGALS3LGALS9LGALS8ALDH1A1
SCHEMBL30854796 0.94 LGALS1 (0.45) LGALS1LGALS3LGALS9LGALS8ALDH1A1
SCHEMBL7117447 0.91 CYP2C19 (0.41) LGALS1LGALS3LGALS9LGALS8LMNA
SCHEMBL1259745 0.91 CYP2C19 (0.41) LGALS1LGALS3LGALS9LGALS8LMNA
SCHEMBL28456180 0.91 CYP2C19 (0.41) LGALS1LGALS3LGALS9LGALS8LMNA
SCHEMBL31121686 0.91 CYP2C19 (0.41) LGALS1LGALS3LGALS9LGALS8LMNA
SCHEMBL1600427 0.91 CYP2C19 (0.41) LGALS1LGALS3LGALS9LGALS8LMNA
SCHEMBL1259125 0.91 CYP2C19 (0.41) LGALS1LGALS3LGALS9LGALS8LMNA
SCHEMBL1259123 0.91 CYP2C19 (0.41) LGALS1LGALS3LGALS9LGALS8LMNA
SCHEMBL1259494 0.91 CYP2C19 (0.41) LGALS1LGALS3LGALS9LGALS8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 US disclosed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 US disclosed
EP-1778709-B1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RES INST LTD (HU) 2008-05-28 EP disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF CFTR, AREG, STS LGALS1 72/4885LGALS3 147/4885LGALS9 220/4885
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof CFTR, AREG, STS LGALS1 72/4885LGALS3 147/4885LGALS9 220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.