Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 6/20 | 0.52 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.46 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.46 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.46 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 3/20 | 0.41 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.40 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.40 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.40 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | GJA1 | P17302 | 1/20 | 0.39 |
| ▸ | GJB2 | P29033 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17822275 | 1.00 | SSTR4 (0.52) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL23319661 | 0.97 | SSTR4 (0.52) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL14672596 | 0.89 | SSTR4 (0.53) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL13402468 | 0.88 | NT5E (0.55) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL9210267 | 0.88 | NT5E (0.55) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL13857154 | 0.88 | NT5E (0.55) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL24107980 | 0.85 | SSTR4 (0.51) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL23603474 | 0.85 | NT5E (0.52) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL17822287 | 0.85 | SSTR4 (0.61) | SSTR4SSTR5SSTR1SSTR2SSTR3 | |
| SCHEMBL23319660 | 0.84 | SSTR4 (0.52) | SSTR4SSTR5SSTR1SSTR2SSTR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10188718-B2 | Vaccines against Streptococcus pneumoniae serotype 4 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2019-01-29 | — | — | US | disclosed |
| EP-3230297-B1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 | MAX PLANCK GESELLSCHAFT (DE) | 2018-10-17 | — | — | EP | disclosed |
| US-20170333545-A1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-11-23 | — | — | US | disclosed |
| EP-3230297-A1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016091399-A1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170333545-A1 | VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 | NEU4, PA2G4, STT3B | SSTR4 420/4885SSTR5 1328/4885SSTR1 2461/4885 |
| US-10188718-B2 | Vaccines against Streptococcus pneumoniae serotype 4 | NEU4, PA2G4, STT3B | SSTR4 420/4885SSTR5 1328/4885SSTR1 2461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.