SCHEMBL17822287

SCHEMBL17822287

CCS[C@@H]1O[C@H](COCc2ccccc2)[C@H](O)[C@H](OCc2ccc3ccccc3c2)[C@H]1OCc1ccc2ccccc2c1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 6/20 0.61
SSTR5 P35346 11/20 0.55
SSTR3 P32745 6/20 0.55
SSTR2 P30874 4/20 0.55
SSTR1 P30872 2/20 0.55
GJA1 P17302 1/20 0.44
GJB2 P29033 1/20 0.44
MCHR1 Q99705 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14672596 0.91 SSTR4 (0.53) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL6767463 0.91 SSTR4 (0.49) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL19276600 0.91 SSTR4 (0.49) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL19276601 0.91 SSTR4 (0.49) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL6952281 0.86 SSTR4 (0.47) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL17822275 0.85 SSTR4 (0.52) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL17822274 0.85 SSTR4 (0.52) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL8630331 0.83 GJB2 (0.45) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL23319661 0.83 SSTR4 (0.52) SSTR4SSTR5SSTR3SSTR2SSTR1
SCHEMBL19272030 0.82 SSTR4 (0.45) SSTR4SSTR5SSTR3SSTR2SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10188718-B2 Vaccines against Streptococcus pneumoniae serotype 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2019-01-29 US disclosed
EP-3230297-B1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX PLANCK GESELLSCHAFT (DE) 2018-10-17 EP disclosed
US-20170333545-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-11-23 US disclosed
EP-3230297-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2017-10-18 EP disclosed
WO-2016091399-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2016-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170333545-A1 VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE SEROTYPE 4 NEU4, PA2G4, STT3B SSTR4 420/4885SSTR5 1328/4885SSTR3 1731/4885
US-10188718-B2 Vaccines against Streptococcus pneumoniae serotype 4 NEU4, PA2G4, STT3B SSTR4 420/4885SSTR5 1328/4885SSTR3 1731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.