Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19665777 | 1.00 | MMP2 (0.53) | MMP2L3MBTL1ALDH1A1KMT2ARAB9A | |
| SCHEMBL5497278 | 1.00 | MMP2 (0.53) | MMP2L3MBTL1ALDH1A1KMT2ARAB9A | |
| SCHEMBL5497274 | 1.00 | MMP2 (0.53) | MMP2L3MBTL1ALDH1A1KMT2ARAB9A | |
| SCHEMBL5497267 | 1.00 | MMP2 (0.53) | MMP2L3MBTL1ALDH1A1KMT2ARAB9A | |
| SCHEMBL17147372 | 0.87 | MAPT (0.48) | L3MBTL1ALDH1A1KMT2ACA12CA9 | |
| SCHEMBL15833066 | 0.87 | MAPT (0.48) | L3MBTL1ALDH1A1KMT2ACA12CA9 | |
| SCHEMBL9379038 | 0.87 | POLB (0.58) | MMP2L3MBTL1ALDH1A1KMT2ACA12 | |
| SCHEMBL9215362 | 0.87 | POLB (0.58) | MMP2L3MBTL1ALDH1A1KMT2ACA12 | |
| SCHEMBL21551179 | 0.87 | POLB (0.58) | MMP2L3MBTL1ALDH1A1KMT2ACA12 | |
| SCHEMBL11458196 | 0.87 | POLB (0.58) | MMP2L3MBTL1ALDH1A1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348375-A1 | DISLODGEMENT AND RELEASE OF HSC FROM THE BONE MARROW STEM CELL NICHE USING ALPHA9 INTEGRIN ANTAGONISTS | COMMW SCIENT IND RES ORG (AU) | 2017-12-07 | — | — | US | disclosed |
| EP-3229797-A1 | DISLODGEMENT AND RELEASE OF HSC FROM THE BONE MARROW STEM CELL NICHE USING ALPHA9 INTEGRIN ANTAGONISTS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016090403-A1 | DISLODGEMENT AND RELEASE OF HSC FROM THE BONE MARROW STEM CELL NICHE USING ALPHA9 INTEGRIN ANTAGONISTS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2016-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348375-A1 | DISLODGEMENT AND RELEASE OF HSC FROM THE BONE MARROW STEM CELL NICHE USING ALPHA9 INTEGRIN ANTAGONISTS | CXCL12, BST2, CCR9 | MMP2 1492/4885L3MBTL1 568/4885ALDH1A1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.