Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MMP3 | P08254 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15833066 | 1.00 | MAPT (0.48) | MAPTMMP3MMP1MMP7ADAM17 | |
| SCHEMBL21716578 | 0.87 | MMP3 (0.47) | MAPTMMP3MMP1MMP7ADAM17 | |
| SCHEMBL5497274 | 0.87 | MMP2 (0.53) | MAPTMMP1ADAM17ALDH1A1L3MBTL1 | |
| SCHEMBL5497278 | 0.87 | MMP2 (0.53) | MAPTMMP1ADAM17ALDH1A1L3MBTL1 | |
| SCHEMBL17822348 | 0.87 | MMP2 (0.53) | MAPTMMP1ADAM17ALDH1A1L3MBTL1 | |
| SCHEMBL19665777 | 0.87 | MMP2 (0.53) | MAPTMMP1ADAM17ALDH1A1L3MBTL1 | |
| SCHEMBL5497267 | 0.87 | MMP2 (0.53) | MAPTMMP1ADAM17ALDH1A1L3MBTL1 | |
| SCHEMBL9215362 | 0.86 | POLB (0.58) | MMP1ADAM17ALDH1A1HTTL3MBTL1 | |
| SCHEMBL9379038 | 0.86 | POLB (0.58) | MMP1ADAM17ALDH1A1HTTL3MBTL1 | |
| SCHEMBL21551179 | 0.86 | POLB (0.58) | MMP1ADAM17ALDH1A1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284375-A1 | HETEROCYCLIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | AJINOMOTO CO., INC. (JP) | 2015-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150284375-A1 | HETEROCYCLIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | TRPA1, TRPV1, TRPV2 | MAPT 1391/4885MMP3 2639/4885MMP1 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.