Sugi Predict

Sugi Predict / Compounds / SCHEMBL17824014

SCHEMBL17824014

SCHEMBL17824014

CN(Cc1ccccc1)C[C@H](O)CO

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DNM1 Q05193 1/20 0.59
▸ AGER Q15109 1/20 0.52
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48
▸ CARM1 Q86X55 1/20 0.47
▸ PRMT6 Q96LA8 1/20 0.47
▸ PRMT8 Q9NR22 1/20 0.47
▸ ALDH1A1 P00352 4/20 0.47
▸ TSHR P16473 2/20 0.47
▸ KDM4E B2RXH2 3/20 0.47
▸ SMN1; SMN2 Q16637 3/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ LMNA P02545 2/20 0.46
▸ USP2 O75604 1/20 0.46
▸ CYP3A4 P08684 1/20 0.46
▸ MAOA P21397 1/20 0.46
▸ MAOB P27338 1/20 0.46
▸ PYCR1 P32322 1/20 0.46
▸ PRMT5 O14744 1/20 0.45
▸ WDR77 Q9BQA1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL721952 1.00 DNM1 (0.59) DNM1AGERMEN1KMT2ACARM1
SCHEMBL17823521 1.00 DNM1 (0.59) DNM1AGERMEN1KMT2ACARM1
SCHEMBL10184760 0.86 DNM1 (0.56) DNM1AGERMEN1KMT2ACARM1
SCHEMBL14923120 0.85 DNM1 (0.59) DNM1AGERMEN1KMT2ACARM1
SCHEMBL20213727 0.85 DNM1 (0.59) DNM1AGERMEN1KMT2ACARM1
SCHEMBL2098163 0.84 DNM1 (0.57) DNM1AGERMEN1KMT2ACARM1
SCHEMBL1022224 0.84 DNM1 (0.57) DNM1AGERMEN1KMT2ACARM1
SCHEMBL12892465 0.84 POLB (0.44) DNM1AGERMEN1KMT2AALDH1A1
SCHEMBL2098159 0.84 DNM1 (0.57) DNM1AGERMEN1KMT2ACARM1
SCHEMBL9700093 0.82 DNM1 (0.55) DNM1AGERMEN1KMT2ACARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630663-B2 Aqueous polyurethane resin dispersion AGFA NV (BE) 2026-05-19 — — US disclosed
EP-3717536-B1 AQUEOUS POLYURETHANE RESIN DISPERSION AGFA NV (BE) 2025-08-13 — — EP disclosed
US-20250145628-A1 PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF NOVO NORDISK A/S (DK) 2025-05-08 — — US disclosed
CN-115667339-B Aqueous polyurethane resin dispersion 爱克发有限公司 2025-02-25 — — CN disclosed
CN-119301126-A Pyrazolopyrimidine compound, composition containing pyrazolopyrimidine compound and application of pyrazolopyrimidine compound 诺和诺德股份有限公司 2025-01-10 — — CN disclosed
EP-4479402-A1 PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF Novo Nordisk A/S (DK) 2024-12-25 — — EP disclosed
EP-3717534-B1 AQUEOUS POLYURETHANE RESIN DISPERSION AGFA NV (BE) 2024-05-08 — — EP disclosed
EP-4165097-B1 AQUEOUS POLYURETHANE RESIN DISPERSION AGFA NV (BE) 2024-03-20 — — EP disclosed
US-11802205-B2 Aqueous polyurethane resin dispersion AGFA NV (BE) 2023-10-31 — — US disclosed
WO-2023155004-A1 PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF INVERSAGO PHARMA INC. (CA) 2023-08-24 — — WO disclosed
US-20180118731-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES BAYER AKTIENGESELLSCHAFT (DE) 2018-05-03 — — US disclosed
US-20180093980-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES EVOTEC AG (DE) 2018-04-05 — — US disclosed
US-20180093980-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES EVOTEC AG (DE) 2018-04-05 — — US disclosed
US-20180093980-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES EVOTEC AG (DE) 2018-04-05 — — US disclosed
US-20180072713-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES EVOTEC AG (DE) 2018-03-15 — — US disclosed
US-20180072713-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES EVOTEC AG (DE) 2018-03-15 — — US disclosed
US-20180072713-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES EVOTEC AG (DE) 2018-03-15 — — US disclosed
EP-3230281-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES Bayer Aktiengesellschaft (DE) 2017-10-18 — — EP disclosed
WO-2016091776-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES EVOTEC AG (DE) 2016-06-16 — — WO disclosed
WO-2016091776-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES EVOTEC AG (DE) 2016-06-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180093980-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES NAT1, HNMT, PMP22 DNM1 3740/4885AGER 2724/4885MEN1 568/4885
US-20180118731-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES NAT1, HNMT, PMP22 DNM1 3740/4885AGER 2724/4885MEN1 568/4885
US-20250145628-A1 PYRAZOLOPYRIMIDINES, COMPOSITIONS COMPRISING THEM AND USES THEREOF CNR1, CNR2, TRPV1 DNM1 1417/4885AGER 3089/4885MEN1 2114/4885
US-12630663-B2 Aqueous polyurethane resin dispersion PUF60, PCMT1, EED DNM1 3071/4885AGER 4483/4885MEN1 4498/4885
US-20180072713-A1 1,3-THIAZOL-2-YL SUBSTITUTED BENZAMIDES NAT1, HNMT, PMP22 DNM1 3740/4885AGER 2724/4885MEN1 568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.