Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984107 | 0.80 | ALDH1A1 (0.48) | HRH3ATMPOLBCYP1A2TDP1 | |
| SCHEMBL9737159 | 0.79 | ALDH1A1 (0.40) | POLBCYP1A2TDP1ALDH1A1TSHR | |
| SCHEMBL26287179 | 0.79 | — | — | |
| SCHEMBL23179813 | 0.79 | HRH3 (0.40) | HRH3 | |
| SCHEMBL1943559 | 0.78 | HRH3 (0.45) | HRH3ATMPOLBCYP1A2TDP1 | |
| SCHEMBL680054 | 0.78 | CYP1A2 (0.54) | HRH3CYP1A2TDP1ALDH1A1 | |
| SCHEMBL16133056 | 0.77 | ATM (0.38) | HRH3ATMPOLBALDH1A1 | |
| SCHEMBL20329945 | 0.76 | HRH3 (0.40) | HRH3ATMPOLBCYP1A2TDP1 | |
| SCHEMBL10313044 | 0.76 | ATM (0.41) | HRH3ATMPOLBCYP1A2TDP1 | |
| SCHEMBL4914434 | 0.76 | HRH3 (0.40) | HRH3ATMPOLBCYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4199968-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | Ambrx, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040596-A1 | ANTIBODY-TLR AGONIST CONJUGATES, METHODS AND USES THEREOF | AMBRX, INC. (US) | 2022-02-24 | — | — | WO | disclosed |
| WO-2018169880-A1 | DUAL MAGL AND FAAH INHIBITORS | ABIDE THERAPEUTICS, INC. (US) | 2018-09-20 | — | — | WO | disclosed |
| EP-3292113-A1 | PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS | Regenacy Pharmaceuticals, LLC (US) | 2018-03-14 | — | — | EP | disclosed |
| WO-2016094824-A1 | PIPERIDINE DERIVATIVES AS HDAC1/2 INHIBITORS | ACETYLON PHARMACEUTICALS, INC. (US) | 2016-06-16 | — | — | WO | disclosed |