SCHEMBL9737159

SCHEMBL9737159

O=C(Cl)N1CCN(C(=O)Cl)CC1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
POLB P06746 2/20 0.38
TDP1 Q9NUW8 2/20 0.36
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 3/20 0.35
MEN1 O00255 2/20 0.35
KDM4E B2RXH2 1/20 0.35
USP2 O75604 1/20 0.35
LMNA P02545 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TSHR P16473 1/20 0.33
GAA P10253 1/20 0.32
TP53 P04637 1/20 0.32
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26287179 1.00
Hydrochloric Acid SCHEMBL11450245 0.96 ALDH1A1 (0.38) ALDH1A1POLBTDP1CYP1A2KMT2A
SCHEMBL1723498 0.87 ALDH1A1 (0.33) ALDH1A1POLBTDP1CYP1A2
SCHEMBL9596694 0.86
SCHEMBL134037 0.86
SCHEMBL14275099 0.85 ALDH1A1 (0.62) ALDH1A1POLBKMT2AMEN1LMNA
SCHEMBL1203272 0.85 CYP1A2 (0.59) ALDH1A1POLBTDP1CYP1A2KMT2A
Hydrochloric Acid SCHEMBL19210209 0.85 ALDH1A1 (0.32) ALDH1A1POLB
SCHEMBL19486 0.85 CYP1A2 (0.59) POLBTDP1CYP1A2KMT2AMEN1
SCHEMBL14001945 0.85 HTR1A (0.41) ALDH1A1POLBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10858589-B2 Polymerizable liquid crystal compound, polymerizable composition, and film FUJIFILM CORPORATION (JP) 2020-12-08 US disclosed
US-20180171232-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, AND FILM FUJIFILM CORPORATION (JP) 2018-06-21 US disclosed
US-20180171232-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, AND FILM FUJIFILM CORPORATION (JP) 2018-06-21 US disclosed
US-5152901-A Highly crosslinked, chlorine-resistant, supported thin film comprising a piperazine monomer; separation of alkaline salts and alkali salts under pressure IONICS, INCORPORATED (US) 1992-10-06 US disclosed
US-4913816-A AMINE CROSSLINKED MULTILAYER POLYMER IONICS INCORPORATED (US) 1990-04-03 US disclosed
US-4758652-A Process for preparing oligomers and telechels having carboxy-piperazine units, and new oligomers and telechels of poly(carboxypiperazine) BAYER AG (DE) 1988-07-19 US disclosed
US-4737325-A CROSSLINKING OF POLYVINYL ALCOHOL AND AMINO COMPOUND NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1988-04-12 US disclosed
EP-0061782-B1 COMPOSITE SEMIPERMEABLE MEMBRANE AND PROCESS FOR PREPARATION THEREOF NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-06-24 EP disclosed
EP-0224176-A1 Process for preparing oligomers and telechelics with carboxy-piperazine units, and oligomers and telechelics of poly(carboxypiperazine) BAYER AG (DE) 1987-06-03 EP disclosed
US-4619767-A POLYVINYL ALCOHOL MODIFIED WITH DIAMINO COMPOUND AND CROSSLINKING AGENT NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1986-10-28 US disclosed
US-4175178-A NONFLAMMABLE FILMS AND FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1979-11-20 US disclosed
US-4175180-A FILMS OR FILAMENTS, NONFLAMMABLE S.A. TEXACO BELGIUM N.V. (BE) 1979-11-20 US disclosed
US-4172935-A FILMS, FILAMENTS S.A TEXACO BELGIUM N.V. (BE) 1979-10-30 US disclosed
US-4165424-A FILMS, FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1979-08-21 US disclosed
US-4144342-A ANTIARTHRITIC AND ANTIINFLAMMATORY AGENTS MERCK & CO., INC. (US) 1979-03-13 US disclosed
US-4142979-A LUBRICATING COMPOSITIONS CONTAINING BISPIPERAZIDO PHOSPHORUS AND TRISPIPERAZIDO PHOSPHORUS COMPOUNDS S.A. TEXACO BELGIUM N.V. (BE) 1979-03-06 US disclosed
US-4098768-A FILMS, FILAMENTS S.A. TEXACO BELGIUM N.V. (BE) 1978-07-04 US disclosed
US-4061759-A ANTIINFLAMMATORY, ARTHRITIS MERCK & CO., INC. (US) 1977-12-06 US disclosed
US-4057637-A RHEUMATOID ARTHRITIS MERCK & CO., INC. (US) 1977-11-08 US disclosed
US-3971797-A ANTIARTHRITIC MERCK & CO., INC. (US) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180171232-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, POLYMERIZABLE COMPOSITION, AND FILM SP1, CCNA1, LMNA ALDH1A1 2121/4885POLB 2269/4885TDP1 1361/4885
US-10858589-B2 Polymerizable liquid crystal compound, polymerizable composition, and film SP1, CCNT1, CCND1 ALDH1A1 2134/4885POLB 2043/4885TDP1 1280/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.