SCHEMBL1781491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4550899	0.90	TSHR (0.40)	PIK3CGHDAC1HDAC6LMNAGAA
	SCHEMBL1781189	0.89	RAB9A (0.38)	PIK3CGPIK3CAPIK3CDPIK3CBHDAC1
	SCHEMBL13690398	0.88	PIK3CA (0.43)	PIK3CGPIK3CAPIK3CDPIK3CBHDAC1
	SCHEMBL1781217	0.88	PIK3CG (0.43)	PIK3CGPIK3CAPIK3CDPIK3CBMAPT
	SCHEMBL1783223	0.88	OGA (0.42)	PIK3CGPIK3CAPIK3CDPIK3CBLMNA
	SCHEMBL1117942	0.88	HTT (0.44)	LMNAMAPTHPGDNPC1ALDH1A1
	SCHEMBL1118042	0.88	PIK3CG (0.38)	PIK3CGPIK3CAPIK3CDPIK3CBLMNA
	SCHEMBL1784359	0.88	HCAR3 (0.40)	PIK3CGPIK3CAPIK3CDPIK3CBLMNA
	SCHEMBL1782298	0.87	PIK3CG (0.50)	PIK3CGPIK3CAPIK3CDPIK3CBLMNA
	SCHEMBL1782049	0.87	PIK3CG (0.38)	PIK3CGPIK3CAPIK3CDPIK3CBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.