Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608969 | 0.80 | SLC6A2 (0.45) | SLC6A2SLC6A3 | |
| SCHEMBL6955106 | 0.70 | — | — | |
| SCHEMBL11312405 | 0.67 | — | — | |
| SCHEMBL4546381 | 0.67 | SLC6A2 (0.34) | SLC6A2SLC6A3 | |
| SCHEMBL27820136 | 0.67 | — | — | |
| SCHEMBL9607530 | 0.62 | SLC6A2 (0.32) | SLC6A2SLC6A3 | |
| SCHEMBL27797613 | 0.62 | — | — | |
| SCHEMBL27896215 | 0.61 | — | — | |
| SCHEMBL27820175 | 0.60 | ALOX5 (0.34) | — | |
| SCHEMBL27799173 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230273-A1 | 2,4-DIOXO-QUINAZOLINE-6-SULFONAMIDE DERIVATIVES AS INHIBITORS OF PARG | Cancer Research Technology Ltd (GB) | 2017-10-18 | — | — | EP | disclosed |
| CN-107207467-A | 2, 4-dioxo-quinazoline-6-sulfonamide derivatives as inhibitors of PARG | 癌症研究科技有限公司 | 2017-09-26 | — | — | CN | disclosed |
| WO-2016092326-A1 | 2,4-DIOXO-QUINAZOLINE-6-SULFONAMIDE DERIVATIVES AS INHIBITORS OF PARG | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-06-16 | — | — | WO | disclosed |