Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799031 | 0.84 | ALOX5 (0.33) | ALOX5TSHR | |
| SCHEMBL27820127 | 0.84 | ALOX5 (0.33) | ALOX5TSHR | |
| SCHEMBL28785808 | 0.81 | ALOX5 (0.32) | ALOX5TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL27797610 | 0.73 | TSHR (0.30) | TSHR | |
| SCHEMBL6955106 | 0.65 | — | — | |
| SCHEMBL27820176 | 0.64 | GABRR1 (0.31) | — | |
| SCHEMBL27797611 | 0.64 | PTGDR2 (0.30) | KDM4E | |
| SCHEMBL27797899 | 0.62 | TSHR (0.30) | TSHR | |
| SCHEMBL11312405 | 0.62 | — | — | |
| SCHEMBL27965548 | 0.62 | HPGD (0.35) | ALOX5MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101891709-A | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2010-11-24 | — | — | CN | claimed |
| CN-101891709-B | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2012-11-21 | — | — | CN | disclosed |
| CN-101891709-A | 5-halogenated methyl-1,2,3-thiadiazole compound and preparation method and use thereof | UNIV NANKAI | 2010-11-24 | — | — | CN | disclosed |