Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1784086 | 0.88 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL1785696 | 0.85 | CYP2D6 (0.51) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL1786261 | 0.85 | TSHR (0.59) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL1785358 | 0.81 | TSHR (0.47) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL24360983 | 0.81 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL1784572 | 0.80 | CYP1A2 (0.49) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL28970002 | 0.79 | CYP2D6 (0.54) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL28354348 | 0.79 | CYP2D6 (0.54) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| SCHEMBL5158787 | 0.79 | TDP1 (0.53) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 | |
| Acetophenone SCHEMBL11149993 | 0.78 | TSHR (0.52) | CYP1A2CYP2D6CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | claimed |
| EP-3486263-A2 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | W.R. Grace & CO. - CONN. (US) | 2019-05-22 | — | — | EP | disclosed |
| EP-2185600-B1 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | GRACE W R & CO (US) | 2018-10-31 | — | — | EP | disclosed |
| US-9796796-B2 | Self-limiting catalyst composition with No silane | W. R. GRACE & CO.-CONN. (US) | 2017-10-24 | — | — | US | disclosed |
| EP-1666505-B1 | CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF | CHINA PETROLEUM & CHEMICAL (CN) | 2016-03-23 | — | — | EP | disclosed |
| CN-103087222-A | Olefin polymerization catalyst, process for producing olefin polymer, polypropylene resin composition and article comprising the same | SUMITOMO CHEMICAL CO | 2013-05-08 | — | — | CN | disclosed |
| US-20130109789-A1 | OLEFIN POLYMERIZATION CATALYST, PROCESS FOR PRODUCING OLEFIN POLYMER, POLYPROPYLENE RESIN COMPOSITION AND ARTICLE COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20110124491-A1 | Self-Limiting Catalyst Composition with No Silane | W. R. GRACE & CO.-CONN. | 2011-05-26 | — | — | US | disclosed |
| EP-2185600-A1 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | Dow Global Technologies Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| CN-101565475-A | Catalyst component and catalyst thereof for olefinic polymerization | CHINA PETROLEUM & CHEMICAL (CN) | 2009-10-28 | — | — | CN | disclosed |
| WO-2009029447-A1 | SELF-LIMITING CATALYST COMPOSITION WITH NO SILANE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2009-03-05 | — | — | WO | disclosed |
| US-7388061-B2 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-06-17 | — | — | US | disclosed |
| US-7332455-B2 | Catalyst component and catalyst for olefin polymerization as well as use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2008-02-19 | — | — | US | disclosed |
| EP-1666505-A1 | CATALYST COMPONENTS CATALYSTS FOR OLEFINIC POLYMERIZATION AND THE USE THEREOF | China Petroleum & Chemical Corporation (CN) | 2006-06-07 | — | — | EP | disclosed |
| US-20050239636-A1 | Solid catalyst component for polymerization of olefins, catalyst comprising the same and use thereof | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-10-27 | — | — | US | disclosed |
| US-20050119427-A1 | Catalyst component and catalyst for olefin polymerization as well as use thereof | BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2005-06-02 | — | — | US | disclosed |
| CN-1446197-A | Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids | WARNER LAMBERT CO (US) | 2003-10-01 | — | — | CN | disclosed |