SCHEMBL28354348

SCHEMBL28354348

CC(C)C(C)(OC(=O)c1ccccc1)C(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2C19 P33261 1/20 0.54
TDP1 Q9NUW8 5/20 0.53
TSHR P16473 4/20 0.53
ALDH1A1 P00352 3/20 0.53
HSD17B10 Q99714 1/20 0.53
LMNA P02545 3/20 0.50
F2 P00734 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.47
MAPT P10636 1/20 0.47
TP53 P04637 1/20 0.47
PDCD1 Q15116 1/20 0.46
CD274 Q9NZQ7 1/20 0.46
MAPK1 P28482 1/20 0.46
HIF1A Q16665 1/20 0.46
ADRB2 P07550 2/20 0.45
ADRB1 P08588 2/20 0.45
ADRB3 P13945 2/20 0.45
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL28286154 0.94 TSHR (0.50) CYP2D6CYP1A2CYP2C19TDP1TSHR
SCHEMBL1784403 0.88 TSHR (0.49) CYP2D6CYP1A2CYP2C19TDP1TSHR
SCHEMBL28970002 0.84 CYP2D6 (0.54) CYP2D6CYP1A2CYP2C19TDP1TSHR
SCHEMBL6948344 0.84 ALDH1A1 (0.54) CYP2D6CYP1A2CYP2C19TDP1TSHR
SCHEMBL1785111 0.81 ALDH1A1 (0.51) CYP2D6CYP1A2CYP2C19TDP1TSHR
SCHEMBL1953844 0.81 TSHR (0.59) CYP2D6CYP1A2CYP2C19TDP1TSHR
Hydrogen Peroxide SCHEMBL28425777 0.81 TDP1 (0.64) CYP2D6CYP1A2CYP2C19TDP1TSHR
SCHEMBL260960 0.81 TDP1 (0.64) CYP2D6CYP1A2CYP2C19TDP1TSHR
SCHEMBL29199324 0.81 TDP1 (0.64) CYP2D6CYP1A2CYP2C19TDP1TSHR
SCHEMBL1786261 0.81 TSHR (0.59) CYP2D6CYP1A2CYP2C19TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110799179-A Solid composition comprising iodine reagent and sodium chloride with improved water solubility and antiviral and antibacterial composition for eye, oral cavity, nasal cavity or inhalation comprising aqueous solution thereof 富陆凯米有限责任公司 2020-02-14 CN disclosed