Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 9/20 | 0.42 |
| ▸ | MAOA | P21397 | 7/20 | 0.42 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17968760 | 1.00 | CAPN1 (0.46) | CAPN1KDM1AMAOARCOR1KDM1B | |
| SCHEMBL17968761 | 1.00 | CAPN1 (0.46) | CAPN1KDM1AMAOARCOR1KDM1B | |
| SCHEMBL17825399 | 1.00 | CAPN1 (0.46) | CAPN1KDM1AMAOARCOR1KDM1B | |
| SCHEMBL17968791 | 0.92 | ITGB3 (0.49) | KDM1AMAOARCOR1KDM1B | |
| SCHEMBL17968792 | 0.92 | ITGB3 (0.49) | KDM1AMAOARCOR1KDM1B | |
| SCHEMBL17825541 | 0.92 | ITGB3 (0.49) | KDM1AMAOARCOR1KDM1B | |
| SCHEMBL19465509 | 0.92 | CTSB (0.41) | KDM1AMAOARCOR1KDM1BCTSL | |
| SCHEMBL17968873 | 0.92 | CTSB (0.41) | KDM1AMAOARCOR1KDM1BCTSL | |
| SCHEMBL17968874 | 0.92 | CTSB (0.41) | KDM1AMAOARCOR1KDM1BCTSL | |
| SCHEMBL17834702 | 0.87 | ITGB3 (0.42) | KDM1AMAOACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-A1 | GLP-1 RECEPTOR MODULATORS | Celgene International II Sarl (CH) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |