Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402242 | 1.00 | MAOA (0.35) | MAOAMAOBNOS1CYP1A2CYP2C9 | |
| SCHEMBL2581191 | 0.86 | MAOA (0.32) | MAOAMAOBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27043289 | 0.85 | TDP1 (0.35) | MAOAMAOBNOS1CYP1A2CYP2C9 | |
| SCHEMBL18590211 | 0.83 | ITGA4 (0.36) | CYP1A2CYP2C9CYP2C19HTTMEN1 | |
| SCHEMBL22398849 | 0.83 | CYP2D6 (0.42) | CYP1A2CYP2C9CYP2C19HTTMEN1 | |
| SCHEMBL13138208 | 0.83 | ITGA4 (0.36) | CYP1A2CYP2C9CYP2C19HTTMEN1 | |
| SCHEMBL7871486 | 0.83 | CYP2D6 (0.42) | CYP1A2CYP2C9CYP2C19HTTMEN1 | |
| SCHEMBL18350242 | 0.83 | ITGA4 (0.36) | CYP1A2CYP2C9CYP2C19HTTMEN1 | |
| SCHEMBL17995263 | 0.83 | ITGA4 (0.36) | CYP1A2CYP2C9CYP2C19HTTMEN1 | |
| SCHEMBL17995262 | 0.83 | CYP2D6 (0.42) | CYP1A2CYP2C9CYP2C19HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-A1 | GLP-1 RECEPTOR MODULATORS | Celgene International II Sarl (CH) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |