Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29882115 | 0.75 | CHRM3 (0.50) | OPRM1OPRD1KMT2AKDM4EKCNN4 | |
| SCHEMBL3363882 | 0.71 | CES1 (0.44) | MEN1KMT2AKCNN4CHRM2CHRM1 | |
| SCHEMBL25477181 | 0.71 | ALDH1A1 (0.52) | KMT2AKDM4EKCNN4ALOX15TSHR | |
| Quinoline SCHEMBL27818688 | 0.70 | ALDH1A1 (0.46) | KMT2AKDM4ECHRM2CHRM1CHRM3 | |
| SCHEMBL6372896 | 0.69 | KCNN4 (0.46) | MEN1KMT2AKDM4EKCNN4CHRM2 | |
| SCHEMBL6372894 | 0.69 | KCNN4 (0.46) | MEN1KMT2AKDM4EKCNN4CHRM2 | |
| SCHEMBL17825461 | 0.69 | KDM4E (0.57) | KMT2AKDM4ECHRM2CHRM1CHRM3 | |
| SCHEMBL6372899 | 0.69 | KCNN4 (0.46) | MEN1KMT2AKDM4EKCNN4CHRM2 | |
| SCHEMBL17313147 | 0.68 | CYP1A2 (0.46) | MEN1KMT2AKCNN4ALOX15TSHR | |
| SCHEMBL4205846 | 0.68 | SLC13A5 (0.44) | OPRM1MEN1KMT2AKDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-A1 | GLP-1 RECEPTOR MODULATORS | Celgene International II Sarl (CH) | 2017-10-18 | — | — | EP | disclosed |
| WO-2016094729-A1 | GLP-1 RECEPTOR MODULATORS | CELGENE INTERNATIONAL II SARL (CH) | 2016-06-16 | — | — | WO | disclosed |