SCHEMBL25477181

SCHEMBL25477181

COCC(COC)(C(=O)O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 3/20 0.52
KCNN4 O15554 1/20 0.47
CES1 P23141 1/20 0.43
HIF1A Q16665 2/20 0.42
CYP2C19 P33261 1/20 0.42
CYP1A2 P05177 2/20 0.42
HTT P42858 1/20 0.41
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
HDAC1 Q13547 2/20 0.39
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.37
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC10 Q969S8 1/20 0.37
HDAC11 Q96DB2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28983035 0.91 ALDH1A1 (0.47) ALDH1A1TSHRKCNN4CES1HIF1A
SCHEMBL24781344 0.86 KCNN4 (0.46) ALDH1A1TSHRKCNN4CES1HIF1A
SCHEMBL25477183 0.85 KCNN4 (0.48) ALDH1A1TSHRKCNN4CES1HIF1A
SCHEMBL25477179 0.85 KCNN4 (0.58) ALDH1A1TSHRKCNN4CES1HIF1A
SCHEMBL30967766 0.81 KDM4E (0.39) ALDH1A1TSHRKCNN4CYP1A2MAPT
SCHEMBL11251 0.80 HTT (0.50) ALDH1A1TSHRKCNN4CES1HIF1A
SCHEMBL6372899 0.78 KCNN4 (0.46) ALDH1A1TSHRKCNN4CES1HIF1A
SCHEMBL6372894 0.78 KCNN4 (0.46) ALDH1A1TSHRKCNN4CES1HIF1A
SCHEMBL6372896 0.78 KCNN4 (0.46) ALDH1A1TSHRKCNN4CES1HIF1A
SCHEMBL3363882 0.77 CES1 (0.44) ALDH1A1TSHRKCNN4CES1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023083295-A1 ESTER DERIVATIVES OF N4-HYDROXYCYTIDINE AND USE THEREOF SUZHOU SPRING-SEA BIO-PHARMACEUTICALS CO., LTD. (CN) 2023-05-19 WO disclosed