SCHEMBL17825564

SCHEMBL17825564

CS(=O)(=O)OCCCl.Clc1cccc(Cl)c1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
TSHR P16473 2/20 0.39
ALOX15 P16050 2/20 0.39
ALDH1A1 P00352 2/20 0.39
LMNA P02545 2/20 0.39
USP2 O75604 1/20 0.39
MMP9 P14780 1/20 0.39
PGR P06401 2/20 0.35
CYP3A4 P08684 1/20 0.34
IDO1 P14902 1/20 0.34
AGXT P21549 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA2A P29274 1/20 0.34
ADORA2B P29275 1/20 0.34
ADORA1 P30542 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
FBP1 P09467 1/20 0.34
NR3C1 P04150 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2284428 0.79 TAAR1 (0.49) CYP3A4IDO1AGXT
SCHEMBL6272279 0.78 KDM4E (0.51) KDM4ELMNA
SCHEMBL2734239 0.78
SCHEMBL11266330 0.77 KMT2A (0.52) KDM4ELMNA
SCHEMBL5584320 0.77 TAAR1 (0.46) KDM4ETSHRALOX15ALDH1A1LMNA
SCHEMBL27972546 0.74 ALDH1A1 (0.47) TSHRALDH1A1LMNAUSP2PGR
Dimethylamine SCHEMBL5971936 0.72 USP2 (0.52) KDM4ETSHRALOX15ALDH1A1LMNA
SCHEMBL15842311 0.71 PGR (0.42) ALDH1A1PGRHPGD
SCHEMBL2536519 0.70 ERCC5 (0.50) ALDH1A1HPGD
SCHEMBL4857267 0.69 TAAR1 (0.44) KDM4ETSHRALOX15ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703744-B2 Process for preparation of luliconazole GLENMARK LIFE SCIENCES LIMITED (IN) 2020-07-07 US disclosed
US-20170362212-A1 PROCESS FOR PREPARATION OF LULICONAZOLE GLENMARK LIFE SCIENCES LIMITED (IN) 2017-12-21 US disclosed
EP-3230280-A1 PROCESS FOR PREPARATION OF LULICONAZOLE Glenmark Pharmaceuticals Limited (IN) 2017-10-18 EP disclosed
WO-2016092478-A1 PROCESS FOR PREPARATION OF LULICONAZOLE GLENMARK PHARMACEUTICALS LIMITED (IN) 2016-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170362212-A1 PROCESS FOR PREPARATION OF LULICONAZOLE LSS, CYP51A1, THPO KDM4E 3191/4885TSHR 4190/4885ALOX15 2691/4885
US-10703744-B2 Process for preparation of luliconazole LSS, CYP51A1, THPO KDM4E 3191/4885TSHR 4190/4885ALOX15 2691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.