SCHEMBL17825573

SCHEMBL17825573

O=c1[nH]cnc2c1CN=C2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
PARP1 P09874 3/20 0.37
TSHR P16473 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CHEK1 O14757 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
SRC P12931 4/20 0.36
GAA P10253 1/20 0.36
PDPK1 O15530 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
BCL2 P10415 1/20 0.33
MCL1 Q07820 1/20 0.33
CA12 O43570 1/20 0.33
ALOX15 P16050 1/20 0.33
CA9 Q16790 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
LMNA P02545 1/20 0.32
ADORA2A P29274 1/20 0.32
SLC6A4 P31645 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL856432 0.72 ALDH1A1 (0.39) ALDH1A1PARP1TSHRNPSR1CHEK1
SCHEMBL15864201 0.68 ALDH1A1 (0.39) ALDH1A1PARP1TSHRNPSR1CHEK1
SCHEMBL3131369 0.68 ALDH1A1 (0.30) ALDH1A1TSHRNPSR1CHEK1HTT
Hydrochloric Acid SCHEMBL8486646 0.65 SRC (0.37) ALDH1A1PARP1TSHRNPSR1CHEK1
SCHEMBL3678768 0.64 ALDH1A1 (0.35) ALDH1A1PARP1TSHRNPSR1CHEK1
SCHEMBL3675974 0.64 ALDH1A1 (0.35) ALDH1A1PARP1TSHRNPSR1CHEK1
SCHEMBL1073971 0.64
SCHEMBL15416608 0.62 SRC (0.35) ALDH1A1NPSR1SRCEGFR
SCHEMBL15864203 0.61 SRC (0.40) ALDH1A1PARP1TSHRNPSR1CHEK1
SCHEMBL14309113 0.60 SRC (0.42) ALDH1A1PARP1TSHRNPSR1CHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3230467-A1 METHODS AND COMPOSITIONS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA ELITechGroup B.V. (NL) 2017-10-18 EP claimed
WO-2016094162-A1 METHODS AND COMPOSITIONS FOR DETECTING ANTIBIOTIC RESISTANT BACTERIA ELITECHGROUP B.V. (NL) 2016-06-16 WO claimed