Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1437156 | 0.81 | ALDH1A1 (0.36) | ALDH1A1SRCSMN1; SMN2TSHRPDPK1 | |
| Hydrochloric Acid SCHEMBL8486646 | 0.73 | SRC (0.37) | ALDH1A1SRCSMN1; SMN2TSHRPDPK1 | |
| SCHEMBL3672630 | 0.72 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL17825573 | 0.72 | ALDH1A1 (0.39) | ALDH1A1SRCSMN1; SMN2TSHRPDPK1 | |
| SCHEMBL3678768 | 0.72 | ALDH1A1 (0.35) | ALDH1A1SRCSMN1; SMN2TSHRPDPK1 | |
| SCHEMBL3675974 | 0.72 | ALDH1A1 (0.35) | ALDH1A1SRCSMN1; SMN2TSHRPDPK1 | |
| SCHEMBL15416608 | 0.69 | SRC (0.35) | ALDH1A1SRCNPSR1EGFR | |
| SCHEMBL7419568 | 0.68 | CA9 (0.38) | ALDH1A1SMN1; SMN2TSHRPDPK1PARP1 | |
| SCHEMBL7018235 | 0.68 | ALDH1A1 (0.39) | ALDH1A1SRCSMN1; SMN2TSHRPDPK1 | |
| SCHEMBL856431 | 0.68 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5070441-A | — | — | None | — | — | JP | disclosed |
| EP-3356345-A1 | HETEROARYL DERIVATIVES AS SEPIAPTERIN REDUCTASE INHIBITORS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2018-08-08 | — | — | EP | disclosed |
| EP-2432779-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | Exelixis, Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010135524-A1 | BENZOXAZEPINES BASED P13K/MT0R INHIBITORS AGAINST PROLIFERATIVE DISEASES | EXELIXIS, INC. (US) | 2010-11-25 | — | — | WO | disclosed |
| JP-H0570441-A | PRODUCTION OF CYCLOPENTA(D)PYRIMIDIN-4-ONES | SANKYO CO LTD | 1993-03-23 | — | — | JP | disclosed |