Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NAE1 | Q13564 | 2/20 | 0.34 |
| ▸ | UBA3 | Q8TBC4 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826004 | 0.84 | CDC7 (0.49) | CSF1REGFRADORA3ADORA2AADORA1 | |
| SCHEMBL17825908 | 0.82 | SLC28A2 (0.44) | CSF1REGFRLMNAMAPK1TP53 | |
| SCHEMBL17825943 | 0.80 | TSHR (0.50) | EGFRADORA3ADORA2ALMNACYP1A2 | |
| SCHEMBL12541692 | 0.77 | HIF1A (0.33) | ADORA3ADORA2AADORA1LMNATP53 | |
| SCHEMBL4279999 | 0.76 | GRIN2B (0.41) | LMNATP53 | |
| SCHEMBL14873502 | 0.69 | SLC29A1 (0.76) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL9913215 | 0.69 | SLC29A1 (0.76) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL19583010 | 0.69 | SLC29A1 (0.76) | SLC29A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL17824385 | 0.68 | GRIN2B (0.41) | — | |
| SCHEMBL7665516 | 0.68 | ADORA3 (0.46) | SLC29A1ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229772-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2017-10-18 | — | — | EP | claimed |
| WO-2016091236-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-16 | — | — | WO | claimed |