Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17825908 | 0.83 | SLC28A2 (0.44) | SMN1; SMN2TP53MAPK1LMNAAURKA | |
| SCHEMBL17825952 | 0.80 | CSF1R (0.43) | TSHRTP53MAPK1CYP1A2CYP2D6 | |
| SCHEMBL17826004 | 0.79 | CDC7 (0.49) | EGFRADORA2AADORA3 | |
| SCHEMBL4279999 | 0.74 | GRIN2B (0.41) | SMN1; SMN2TP53LMNAHIF1ARXFP1 | |
| SCHEMBL12541692 | 0.73 | HIF1A (0.33) | SMN1; SMN2TP53LMNAHIF1ARXFP1 | |
| SCHEMBL19583025 | 0.72 | SLC29A1 (0.61) | TSHRHIF1AADORA2AADORA3 | |
| SCHEMBL30410931 | 0.68 | TSHR (1.00) | TSHRHSD17B10SMN1; SMN2TP53MAPK1 | |
| SCHEMBL1442843 | 0.68 | TSHR (1.00) | TSHRHSD17B10SMN1; SMN2TP53MAPK1 | |
| SCHEMBL7204775 | 0.68 | ADRB1 (0.32) | — | |
| SCHEMBL19244785 | 0.66 | TSHR (0.60) | TSHRHSD17B10SMN1; SMN2TP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229772-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | Univerzita Palackého v Olomouci (CZ) | 2017-10-18 | — | — | EP | claimed |
| WO-2016091236-A1 | 6-ARYL-9-GLYCOSYLPURINES AND USE THEREOF | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-16 | — | — | WO | claimed |