SCHEMBL1782648

SCHEMBL1782648

CCC(C)(C)CC(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2612030 0.84 ALDH1A1 (0.41)
SCHEMBL9686294 0.83 TDP1 (0.46)
SCHEMBL17660547 0.81 ALDH1A1 (0.32)
SCHEMBL10473953 0.79 TDP1 (0.37)
SCHEMBL19653730 0.79 TDP1 (0.46)
SCHEMBL13184919 0.79 ALDH1A1 (0.37)
SCHEMBL1784497 0.78 TDP1 (0.41)
SCHEMBL1409381 0.77
SCHEMBL276450 0.77
SCHEMBL14321999 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100249166-A1 DIFFERENTIAL EVAPORATION POTENTIATED DISINFECTANT SYSTEM XY, INC. (US) 2010-09-30 US claimed
EP-0065707-B1 PROCESS FOR THE PREPARATION OF DIMEDONE LONZA AG (CH) 1985-04-17 EP claimed
US-20180056691-A1 INK SET AND IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2018-03-01 US disclosed
US-20170196848-A1 Prodrugs of NH-Acidic Compounds: Ester, Carbonate, Carbamate and Phosphonate Derivatives ALKERMES PHARMA IRELAND LTD (IE) 2017-07-13 US disclosed
US-9585965-B2 Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives ALKERMES PHARMA IRELAND LIMITED (IE) 2017-03-07 US disclosed
US-20160095938-A1 CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS IMMUNOGEN, INC. 2016-04-07 US disclosed
US-9273080-B2 Metal complexes MEREK PATENT GMBH (DE) 2016-03-01 US disclosed
US-20150320875-A1 Prodrugs of NH-Acidic Compounds: Ester, Carbonate, Carbamate and Phosphonate Derivatives ALKERMES PHARMA IRELAND LTD (IE) 2015-11-12 US disclosed
US-9072788-B2 Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives ALKERMES PHARMA IRELAND LIMITED (IE) 2015-07-07 US disclosed
US-20140370011-A1 METHODS OF TREATING OR PREVENTING COGNITIVE IMPAIRMENT USING INDANE ACETIC ACID DERIVATIVES DARA BIOSCIENCES, INC. (US) 2014-12-18 US disclosed
US-8841331-B2 Inhibitors of human immunodeficiency virus replication GILEAD SCIENCES, INC. (US) 2014-09-23 US disclosed
WO-1999014176-A1 METHOD FOR THE GEMINAL DICHLORINATION OF ALKYL METHYL KETONES GREAT LAKES CHEMICAL KONSTANZ GMBH (DE) 1999-03-25 WO disclosed
EP-0531715-B1 Process for producing alcohols and ketones SUMITOMO CHEMICAL CO (JP) 1997-11-05 EP disclosed
US-5426237-A Oxidation of straight, branched or cyclic alkanes and benzene derivatives in presence of transition metal catalyst and aldehyde SUMITOMO CHEMICAL CO., LTD. (JP) 1995-06-20 US disclosed
EP-0531715-A1 Process for producing alcohols and ketones SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-17 EP disclosed
EP-0187216-B1 PROCESS FOR THE PREPARATION OF HALOGENATED 3,3-DIMETHYL-5-HEXEN-2-ONES BAYER AG (DE) 1988-04-27 EP disclosed
EP-0065707-A2 Process for the preparation of dimedone LONZA AG (CH) 1982-12-01 EP disclosed
EP-0065708-A2 Process for the preparation of dimedone LONZA AG (CH) 1982-12-01 EP disclosed
EP-0064634-A1 Process for the preparation of 3,3-dimethyl-glutaric acid LONZA AG (CH) 1982-11-17 EP disclosed
US-4275069-A Anti-diabetic 1,2-dihydro-2-oxo-6-alkyl-nicotinic acids THE UPJOHN COMPANY (US) 1981-06-23 US disclosed