Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826584 | 0.87 | MEN1 (0.65) | SIRT2ALDH1A1KMT2ASMN1; SMN2SIRT1 | |
| SCHEMBL17826583 | 0.87 | ALDH1A1 (0.64) | SIRT2ALDH1A1KMT2AL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL1706823 | 0.86 | SIRT2 (1.00) | SIRT2SIRT1SIRT3 | |
| SCHEMBL13972901 | 0.85 | L3MBTL1 (0.84) | ALDH1A1KMT2AL3MBTL1MAPTLMNA | |
| SCHEMBL17826597 | 0.85 | SIRT2 (0.73) | SIRT2SIRT1SIRT3 | |
| SCHEMBL17826587 | 0.85 | ALDH1A1 (0.60) | SIRT2ALDH1A1CA1CA2CA9 | |
| SCHEMBL17826576 | 0.84 | POLB (0.64) | SIRT2ALDH1A1CA1CA2CA9 | |
| SCHEMBL17826588 | 0.84 | SIRT2 (0.63) | SIRT2SIRT1SIRT3 | |
| SCHEMBL17826598 | 0.84 | SIRT2 (0.77) | SIRT2MAPTSIRT1SIRT3 | |
| SCHEMBL16587385 | 0.84 | ALDH1A1 (0.78) | SIRT2ALDH1A1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365508-B2 | Aroyl thiourea derivatives | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2016-06-14 | — | — | US | disclosed |