SCHEMBL17826636

SCHEMBL17826636

Cc1c(OC(=O)c2ccc(-c3ccc(O)cc3)cc2)ccc(OC(=O)c2ccc(-c3ccc(O)cc3)cc2)c1C

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 1/20 0.59
CA12 O43570 3/20 0.50
CA1 P00915 3/20 0.50
CA2 P00918 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
ESR1 P03372 3/20 0.50
ESR2 Q92731 2/20 0.50
HSD17B1 P14061 1/20 0.50
LMNA P02545 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
POLB P06746 1/20 0.44
ALDH1A1 P00352 2/20 0.43
CHRM1 P11229 1/20 0.43
TSHR P16473 1/20 0.43
SLC6A2 P23975 1/20 0.43
KDR P35968 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777822 0.94 CA1 (0.55) SENP1CA12CA1CA2CA7
SCHEMBL15591334 0.91 ESR2 (0.56) SENP1CA12CA1CA2CA7
SCHEMBL18594949 0.89 NPC1 (0.54) SENP1CA12CA1CA2CA7
SCHEMBL19763403 0.85 SENP1 (0.50) SENP1CA12CA1CA2CA7
SCHEMBL15482301 0.85 KMT2A (0.57) CA12CA1CA2CA7CA9
SCHEMBL767730 0.85 SENP1 (0.50) SENP1CA12CA1CA2CA7
SCHEMBL19763405 0.83 SENP1 (0.51) SENP1CA12CA1CA2CA7
SCHEMBL17826637 0.81 SENP1 (0.46) SENP1CA12CA1CA2CA7
SCHEMBL16351760 0.81 TDP1 (0.57) ESR1ESR2LMNAMEN1KMT2A
SCHEMBL1816359 0.79 ALDH1A1 (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9366898-B2 Liquid crystal display device and method for manufacturing the same BEIJING BOE OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) 2016-06-14 US disclosed