Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15944117 | 0.86 | NR4A2 (0.43) | KMT2AMAPTMEN1ALDH1A1LMNA | |
| SCHEMBL3334684 | 0.85 | AAK1 (0.45) | MTNR1AMTNR1BCTSLCTSSCTSK | |
| SCHEMBL3331422 | 0.84 | MTNR1A (0.57) | KMT2AMAPTMEN1ALDH1A1TDP1 | |
| SCHEMBL15944824 | 0.82 | MTNR1A (0.39) | KMT2AMAPTMEN1GAAMTNR1A | |
| SCHEMBL13301913 | 0.82 | MAPT (0.49) | KMT2AMAPTMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL13301912 | 0.79 | AAK1 (0.45) | MTNR1AMTNR1B | |
| SCHEMBL13302029 | 0.75 | HDAC10 (0.35) | MAPK1MTNR1AMTNR1B | |
| SCHEMBL17826908 | 0.73 | MTNR1A (0.54) | MTNR1AMTNR1BTRPV1 | |
| Trimethylammonium SCHEMBL9095683 | 0.72 | MAPT (0.47) | KMT2AMAPTMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL3333209 | 0.72 | NR4A2 (0.44) | MTNR1AMTNR1BTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121601-B1 | NOVEL INDOLE DERIVATIVES, METHODS FOR PREPARING SAME, AND USE THEREOF PARTICULARLY AS ANTIBACTERIAL AGENTS | Université Joseph Fourier (FR) | 2016-06-15 | — | — | EP | disclosed |