Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 5/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351093 | 0.82 | NAMPT (0.36) | — | |
| SCHEMBL4347399 | 0.71 | L3MBTL1 (0.37) | — | |
| SCHEMBL18855919 | 0.68 | — | — | |
| SCHEMBL29408993 | 0.68 | HSD11B1 (0.42) | SCN9A | |
| SCHEMBL1536149 | 0.68 | L3MBTL1 (0.34) | — | |
| SCHEMBL12389611 | 0.67 | CA12 (0.42) | — | |
| SCHEMBL4350834 | 0.65 | L3MBTL1 (0.34) | — | |
| SCHEMBL4351088 | 0.65 | L3MBTL1 (0.34) | — | |
| SCHEMBL19033759 | 0.60 | CYP2C19 (0.54) | CYP3A4 | |
| SCHEMBL19188365 | 0.58 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3031324-A2 | TRICYCLIC KINASE INHIBITORS | AbbVie Inc. (US) | 2016-06-15 | — | — | EP | disclosed |