Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827804 | 0.85 | PRKAB2 (0.33) | — | |
| SCHEMBL21919557 | 0.85 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP3A4CYP2C9APP | |
| SCHEMBL2741550 | 0.85 | CYP11B1 (0.35) | CYP11B1CYP11B2CYP3A4CYP2C9APP | |
| SCHEMBL20083440 | 0.85 | KDM1A (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL20083474 | 0.85 | CYP11B1 (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL22341768 | 0.84 | CYP11B1 (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL25574557 | 0.83 | CYP11B1 (0.32) | CYP11B1CYP11B2 | |
| SCHEMBL18487477 | 0.82 | CYP11B1 (0.45) | CYP11B1CYP11B2CYP3A4CYP2C9APP | |
| SCHEMBL19500359 | 0.82 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL25574554 | 0.81 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9404038-B2 | Cyclopropyl-bearing liquid crystal compounds and mixtures | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-02 | — | — | US | disclosed |
| US-9404038-B2 | Cyclopropyl-bearing liquid crystal compounds and mixtures | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-08-02 | — | — | US | disclosed |
| US-20160168461-A1 | CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-06-16 | — | — | US | disclosed |
| US-20160168461-A1 | CYCLOPROPYL-BEARING LIQUID CRYSTAL COMPOUNDS AND MIXTURES | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO., LTD. (CN) | 2016-06-16 | — | — | US | disclosed |