Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 3/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19590564 | 0.92 | TSPO (0.64) | TSPO | |
| SCHEMBL17940510 | 0.90 | TSPO (0.85) | TSPO | |
| SCHEMBL16585388 | 0.90 | TSPO (0.85) | TSPO | |
| SCHEMBL415392 | 0.86 | TSPO (0.70) | TSPO | |
| SCHEMBL15101782 | 0.86 | TSPO (0.70) | TSPO | |
| SCHEMBL30106112 | 0.85 | TSPO (0.77) | TSPO | |
| SCHEMBL419235 | 0.85 | TSPO (0.77) | TSPO | |
| SCHEMBL16585506 | 0.85 | TSPO (0.77) | TSPO | |
| SCHEMBL17940513 | 0.85 | TSPO (0.77) | TSPO | |
| SCHEMBL10090113 | 0.84 | TSPO (1.00) | TSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9815785-B2 | Enantiomeric separation and purification of 2,3,4,9-tetrahydro-1H-carbazole-4-carboxylic acid amide derivatives | GE HEALTHCARE LIMITED (GB) | 2017-11-14 | — | — | US | disclosed |
| US-20160168091-A1 | ENANTIOMERIC SEPARATION AND PURIFICATION OF 2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-4-CARBOXYLIC ACID AMIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168091-A1 | ENANTIOMERIC SEPARATION AND PURIFICATION OF 2,3,4,9-TETRAHYDRO-1H-CARBAZOLE-4-CARBOXYLIC ACID AMIDE DERIVATIVES | IDO2, IDO1, TPH2 | TSPO 3560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.