SCHEMBL1782837

SCHEMBL1782837

CC(C)CCC(C)CCCC=O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
HIF1A Q16665 1/20 0.41
TSHR P16473 2/20 0.40
BLM P54132 1/20 0.39
PTPN1 P18031 2/20 0.34
MEN1 O00255 1/20 0.34
CYP3A4 P08684 1/20 0.34
ALOX15 P16050 1/20 0.34
KMT2A Q03164 1/20 0.34
FAAH O00519 2/20 0.33
TRPV1 Q8NER1 2/20 0.33
ACE2 Q9BYF1 1/20 0.32
ADH1B P00325 1/20 0.32
ADH1C P00326 1/20 0.32
ADH1A P07327 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL585190 0.91 LMNA (0.59) LMNAHIF1ATSHRBLMPTPN1
SCHEMBL28922962 0.91 LMNA (0.59) LMNAHIF1ATSHRBLMPTPN1
SCHEMBL3408019 0.85 HIF1A (0.45) LMNAHIF1ATSHRBLMALOX15
SCHEMBL1784683 0.85 LMNA (0.38) LMNAHIF1ATSHRBLMALOX15
SCHEMBL231303 0.85
SCHEMBL3414061 0.84 HIF1A (0.39) LMNAHIF1ATSHRFAAHTRPV1
SCHEMBL18092218 0.84 LMNA (0.64) LMNAHIF1ATSHRBLMPTPN1
SCHEMBL10081315 0.82 TSHR (0.48) LMNAHIF1ATSHRBLMALOX15
SCHEMBL28420777 0.82 HIF1A (0.38) LMNAHIF1ATSHRFAAHTRPV1
SCHEMBL13216003 0.81 TSHR (0.39) LMNAHIF1ATSHRBLMPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8632792-B2 Cooling sensation agent composition and sensory stimulation agent composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-01-21 US disclosed
US-8124562-B2 Thermal transfer ink sheet, ink cartridge, coating composition for dye layer of thermal transfer ink sheet, and thermal transfer recording method FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-8124562-B2 Thermal transfer ink sheet, ink cartridge, coating composition for dye layer of thermal transfer ink sheet, and thermal transfer recording method FUJIFILM CORPORATION (JP) 2012-02-28 US disclosed
US-8114813-B2 Heat transferrable dye in resin containing polyvinyl acetal modified with ketone FUJIFILM CORPORATION (JP) 2012-02-14 US disclosed
US-8114813-B2 Heat transferrable dye in resin containing polyvinyl acetal modified with ketone FUJIFILM CORPORATION (JP) 2012-02-14 US disclosed
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-05-19 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed
US-20090061350-A1 THERMAL TRANSFER INK SHEET, INK CARTRIDGE, COATING COMPOSITION FOR DYE LAYER OF THERMAL TRANSFER INK SHEET, AND THERMAL TRANSFER RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-03-05 US disclosed
US-20090061350-A1 THERMAL TRANSFER INK SHEET, INK CARTRIDGE, COATING COMPOSITION FOR DYE LAYER OF THERMAL TRANSFER INK SHEET, AND THERMAL TRANSFER RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-03-05 US disclosed
US-20080242540-A1 THERMAL TRANSFER INK SHEET, INK CARTRIDGE, COATING COMPOSITION FOR DYE LAYER OF THERMAL TRANSFER INK SHEET, AND THERMAL TRANSFER RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed
US-20080242540-A1 THERMAL TRANSFER INK SHEET, INK CARTRIDGE, COATING COMPOSITION FOR DYE LAYER OF THERMAL TRANSFER INK SHEET, AND THERMAL TRANSFER RECORDING METHOD FUJIFILM CORPORATION (JP) 2008-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110117147-A1 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TRPA1, HRH1, HRH2 LMNA 1708/4885HIF1A 1980/4885TSHR 2479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.