Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.50 |
| ▸ | ADH1B | P00325 | 2/20 | 0.48 |
| ▸ | ADH1C | P00326 | 2/20 | 0.48 |
| ▸ | ADH1A | P07327 | 2/20 | 0.48 |
| ▸ | ADH4 | P08319 | 2/20 | 0.48 |
| ▸ | ADH7 | P40394 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28194813 | 1.00 | TSHR (0.56) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL13309277 | 1.00 | TSHR (0.56) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL13309278 | 1.00 | TSHR (0.56) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL27577002 | 1.00 | TSHR (0.56) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL11358374 | 1.00 | TSHR (0.56) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL1410356 | 0.98 | TSHR (0.52) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL31132197 | 0.92 | TSHR (0.52) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL23925001 | 0.91 | TSHR (0.70) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL9544428 | 0.91 | TSHR (0.70) | TSHRACE2FAAHTRPV1ADH1B | |
| SCHEMBL21380134 | 0.91 | TSHR (0.70) | TSHRACE2FAAHTRPV1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103113295-A | Alkyl-substituted quinolinone compound with side chains as well as preparation method, pharmaceutical composition and application thereof | UNIV CHONGQING TECHNOLOGY | 2013-05-22 | — | — | CN | claimed |
| CN-106999973-A | System and method for discharging edible material | 阿甘芳香和精细化工有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-102241720-B | L-nucleic acid derivative and processes for the synthesis thereof | MITSU CHEMICALS INC | 2014-01-29 | — | — | CN | disclosed |
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| CN-103113295-A | Alkyl-substituted quinolinone compound with side chains as well as preparation method, pharmaceutical composition and application thereof | UNIV CHONGQING TECHNOLOGY | 2013-05-22 | — | — | CN | disclosed |
| CN-101250208-B | L-nucleic acid derivative and processes for the synthesis thereof | MITSU CHEMICALS INC | 2012-06-20 | — | — | CN | disclosed |
| CN-102241720-A | L-nucleic acid derivative and processes for the synthesis thereof | MITSU CHEMICALS INC | 2011-11-16 | — | — | CN | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| EP-1348712-B1 | Processes and intermediates in the synthesis of L-thymidine | MITSUI CHEMICALS INC (JP) | 2011-05-04 | — | — | EP | disclosed |
| CN-101250194-B | L-nucleic acid derivative and processes for the synthesis thereof | MITSUI CHEMICALS INC | 2011-05-04 | — | — | CN | disclosed |
| EP-0251827-B1 | NEW CYCLIC ETHER DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-09-15 | — | — | EP | disclosed |
| CN-1072686-A | Has Pyrmidine nucleoside derivatives of anti-tumor activity and its production and use | SANKYO CO (JP) | 1993-06-02 | — | — | CN | disclosed |
| EP-0536936-A1 | Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use | Sankyo Company Limited (JP) | 1993-04-14 | — | — | EP | disclosed |
| CN-1059720-A | Radicicol derivatives, its preparation method and anti-tumor activity thereof | SANKYO CO (JP) | 1992-03-25 | — | — | CN | disclosed |
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |
| EP-0460950-A1 | Radicicol derivatives, their preparation and their anti-tumour activity | Sankyo Company Limited (JP) | 1991-12-11 | — | — | EP | disclosed |
| EP-0437016-A2 | Lipid A analogues having immunoactivating and anti-tumour activity | Sankyo Company Limited (JP) | 1991-07-17 | — | — | EP | disclosed |
| CN-1052481-A | Lipoid category-A with immunocompetence and anti-tumor activity is like thing | SANKYO CO (JP) | 1991-06-26 | — | — | CN | disclosed |
| US-4891363-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY LIMITED (JP) | 1990-01-02 | — | — | US | disclosed |
| EP-0251827-A2 | New cyclic ether derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | TSHR 2479/4885ACE2 4401/4885FAAH 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.