Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.34 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830467 | 0.90 | RAB9A (0.47) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL19726895 | 0.79 | ENPP2 (0.49) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL14361680 | 0.78 | ENPP2 (0.58) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL14361673 | 0.78 | ENPP2 (0.58) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL19713085 | 0.77 | ENPP2 (0.62) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL19713084 | 0.77 | ENPP2 (0.62) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL19726893 | 0.76 | KDM4E (0.46) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL19713051 | 0.76 | ENPP2 (0.51) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL17830245 | 0.76 | ENPP2 (0.51) | KDM4EALDH1A1ENPP2HPGDALOX12 | |
| SCHEMBL17830431 | 0.74 | ENPP2 (0.54) | KDM4EALDH1A1ENPP2APEX1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094897-A1 | COMPOSITIONS AND METHODS RELATING TO THE TREATMENT OF CANCER, AUTOIMMUNE DISEASE, AND NEURODEGENERATIVE DISEASE | THE JACKSON LABORATORY (US) | 2016-06-16 | — | — | WO | disclosed |