SCHEMBL17830943

SCHEMBL17830943

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4cccc5c4c4ccccc4n5-c4ccc(N(c5ccc(-c6ccccc6)cc5)c5ccc(-c6ccccc6)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
HDAC4 P56524 1/20 0.39
MAPK14 Q16539 1/20 0.35
KMT2A Q03164 2/20 0.34
IL1R1 P14778 1/20 0.34
PDE6D O43924 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
MAPK8 P45983 1/20 0.31
RORC P51449 1/20 0.31
KDM1A O60341 1/20 0.31
APP P05067 1/20 0.31
HTR6 P50406 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17830944 0.99 L3MBTL1 (0.41) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL17877942 0.99 L3MBTL1 (0.41) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL17830953 0.97 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL17830950 0.97 L3MBTL1 (0.42) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL17877961 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL16158379 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL16158300 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL17877965 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL17830970 0.97 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4MAPK14
SCHEMBL17830945 0.96 L3MBTL1 (0.43) L3MBTL1KDM4EATMHDAC4MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160172597-A1 CARBAZOLE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, AND ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-16 US disclosed
US-20160172597-A1 CARBAZOLE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, AND ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160172597-A1 CARBAZOLE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, AND ORGANIC ELECTROLUMINESCENT DEVICE LEF1, LAMTOR3, EZH2 L3MBTL1 1169/4885KDM4E 1810/4885ATM 3383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.