SCHEMBL1783186

SCHEMBL1783186

C=Cc1ccc([SiH](C)C)cc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.58
TSHR P16473 1/20 0.43
HDAC8 Q9BY41 2/20 0.42
TDP1 Q9NUW8 2/20 0.38
TP53 P04637 1/20 0.34
TRPA1 O75762 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Oxide SCHEMBL3761538 0.84 ALDH1A1 (0.41) ALDH1A1TSHRHDAC8
SCHEMBL30437098 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL30792532 0.80 ALDH1A1 (0.52) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL29364676 0.78 NFE2L2 (0.39) TRPA1
SCHEMBL8992212 0.78 ALDH1A1 (0.65) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL28401796 0.77 ALDH1A1 (0.48) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL20958703 0.77 ALDH1A1 (0.48) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL473081 0.76 ALDH1A1 (1.00) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL7639 0.76 ALDH1A1 (1.00) ALDH1A1TSHRHDAC8TDP1TP53
SCHEMBL148576 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 334 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119978228-A Preparation method of flexible material for violent sorting and high-temperature early warning in fire material evidence transportation 应急管理部沈阳消防研究所 2025-05-13 CN claimed
CN-119708755-A Self-healing type fire physical evidence logistics transportation buffer material and preparation method thereof 应急管理部沈阳消防研究所 2025-03-28 CN claimed
CN-119431666-A High cis-polybutadiene elastomer and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-117820746-B Composite PE plastic and preparation process thereof 贵州博裕新能源科技有限公司 2024-12-03 CN claimed
CN-118221847-A Thermosetting resin, resin composition and application thereof 华为技术有限公司 2024-06-21 CN claimed
CN-117820746-A Composite PE plastic and preparation process thereof 广东定通实业有限公司 2024-04-05 CN claimed
CN-117586681-A Preparation method of bottom anti-reflection coating resin with high peel strength 苏州威迈芯材半导体有限公司 2024-02-23 CN claimed
CN-115536762-A Differential photoresponse and isomerization reversible liquid crystal grafted modified polystyrene with wide liquid crystal temperature domain and preparation method thereof 大连理工大学 2022-12-30 CN claimed
CN-111801358-B Method for producing polymer and flow reaction system for producing polymer 富士胶片株式会社 2022-12-16 CN claimed
CN-113061203-B Catalyst and preparation method thereof, and preparation method of styrene monomer isotactic polymer 中国科学院长春应用化学研究所 2022-03-29 CN claimed
CN-103819593-A Hydrosilicon functionalized rare earth syndiotactic polystyrene and preparation method UNIV DALIAN TECH 2014-05-28 CN claimed
CN-102321214-B Polyethylene containing silicon-hydrogen reactive group on side group and preparation method thereof UNIV DALIAN TECH 2014-04-02 CN claimed
US-20130264287-A1 GRAFTED MEMBRANES AND SUBSTRATES HAVING SURFACES WITH SWITCHABLE SUPEROLEOPHILICITY AND SUPEROLEOPHOBICITY AND APPLICATIONS THEREOF KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2013-10-10 US claimed
US-20130240758-A1 PLASMONIC ASSISTED SYSTEMS AND METHODS FOR INTERIOR ENERGY-ACTIVATION FROM AN EXTERIOR SOURCE IMMUNOLIGHT, LLC (US) 2013-09-19 US claimed
WO-2013046056-A2 GRAFTED MEMBRANES AND SUBSTRATES HAVING SURFACES WITH SWITCHABLE SUPEROLEOPHILICITY AND SUPEROLEOPHOBICITY AND APPLICATIONS THEREOF KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2013-04-04 WO claimed
US-8318191-B2 Porous material having hierarchical porous structure and preparation method thereof KOREAN INSTITUTE OF MACHINERY & MATERIALS (KR) 2012-11-27 US claimed
CN-102321214-A Polyethylene containing silicon-hydrogen reactive group on side group and preparation method thereof UNIV DALIAN TECH 2012-01-18 CN claimed
US-20100010513-A1 POROUS MATERIAL HAVING HIERARCHICAL POROUS STRUCTURE AND PREPARATION METHOD THEREOF KOREAN INSTITUTE OF MACHINERY & MATERIALS (KR) 2010-01-14 US claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed