Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | GBA1 | P04062 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | MANBA | O00462 | 2/20 | 0.47 |
| ▸ | IDUA | P35475 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PYGB | P11216 | 2/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | PYGM | P11217 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconolactone SCHEMBL15320 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL13695616 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL19068026 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL221828 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL12377168 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL24637666 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL2461264 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL13176828 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL15631262 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA | |
| Gluconolactone SCHEMBL7152056 | 1.00 | LMNA (1.00) | LMNAGBA1HIF1AMANBAIDUA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160168183-A1 | Conjugates Containing Hydrophilic Spacer Linkers | ENDOCYTE INC (US) | 2016-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168183-A1 | Conjugates Containing Hydrophilic Spacer Linkers | CD44, HAVCR2, HCAR1 | LMNA 903/4885GBA1 309/4885HIF1A 411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.